Publications by authors named "Y Brito-Casillas"
For thousands of years, has been widely used as an herbal medicine to treat some diseases and symptoms, including respiratory, gastrointestinal and urogenital ailments. The present study was adapted to document and assemble existing information about and its evidence-based ethnopharmacological activities, with brief reviews on the description, geographical distribution, ecology, medical uses and phytochemistry. A literature review and information up to 2024 was performed in various scientific databases, including PubMed, Science Direct and Google Scholar.
View Article and Find Full Text PDFIn Brief: Fertility has decreased due to advanced maternal age and the rising prevalence of the metabolic syndrome. Using quantitative image analysis methods, we show that these factors are associated with delayed preimplantation embryo development in a mouse model.
Abstract: Delayed maternal age, obesity and diabetes are associated with reduced fertility.
The p.(Tyr400_Phe402del) mutation in the LDL receptor () gene is the most frequent cause of familial hypercholesterolaemia (FH) in Gran Canaria. The aim of this study was to determine the age and origin of this prevalent founder mutation and to explore its functional consequences.
View Article and Find Full Text PDFBackground: Obesity has been proposed as an independently risk factor for chronic kidney disease (CKD) in people, but its role in feline kidney function is unknown.
Objective: Obesity has been proposed as an independent risk factor for chronic kidney disease (CKD) in people, but its role in feline kidney function is unknown. This study prospectively evaluated the effect of overweight on the concentration of symmetric dimethylarginine (SDMA) and creatinine in a cohort of healthy cats.
Article Synopsis
- Hepatocellular carcinoma (HCC) is a severe type of liver cancer, but the cellular processes behind its progression are not fully understood, particularly regarding the SOCS2 protein's role.
- In experiments with mice, researchers found that those lacking SOCS2 had more severe liver tumors, increased inflammation, and higher levels of certain proteins linked to cancer growth, suggesting SOCS2 has a protective function.
- Additionally, lower levels of SOCS2 were observed in HCC patients compared to healthy livers, indicating it could be a potential biomarker and target for HCC treatment.