Publications by authors named "Y Braun"

Background: Necrotizing enterocolitis (NEC) is a common disease in premature infants. If conservative treatment does not respond, surgical removal of the necrotic section of bowel is common practice. This study investigates whether there is a correlation between the histopathological findings and the postoperative clinical course of the children who have undergone surgery.

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Article Synopsis
  • Classical Hirschsprung disease (HD) is characterized by the lack of nerve cells in the colon, diagnosed via rectal biopsy showing aganglionosis and cholinergic hyperinnervation, but biopsy methods can affect accuracy.
  • A study analyzed 190 samples from patients using digital imaging software to assess acetylcholinesterase (AChE) staining and utilized machine learning to detect patterns of hyperinnervation.
  • Results indicated that AChE staining was significantly higher in HD patients than in healthy individuals, and machine learning models demonstrated high accuracy in diagnosing HD, particularly when excluding non-rectal samples.
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This is a report of successful treatment of an abdominal aortic aneurysm via standard endovascular aortic repair with an ultra-low dose (ULD) of 2.4 Gy∗cm using the latest imaging software in a hybrid operating room. To the best of our knowledge, no case has yet been reported achieving a successful outcome with such ULD values to date.

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Background: Acute graft-versus-host disease (aGvHD) is a major cause of death for patients following allogeneic hematopoietic stem cell transplantation (HSCT). Effective management of moderate to severe aGvHD remains challenging despite recent advances in HSCT, emphasizing the importance of prophylaxis and risk factor identification.

Methods: In this study, we analyzed data from 1479 adults who underwent HSCT between 2005 and 2017 to investigate the effects of aGvHD prophylaxis and time-dependent risk factors on the development of grades II-IV aGvHD within 100 days post-HSCT.

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