Publications by authors named "Y Benito"
Article Synopsis
- - Pregnancy in multiple sclerosis (MS) patients is generally supported, but many delay motherhood to ensure low disease activity, which can affect fertility and the need for assisted reproductive technology (ART).
- - A group of seven experts conducted discussions and literature reviews to better understand fertility, pregnancy impacts, treatment during pregnancy, and ART options for MS patients.
- - The review emphasizes the importance of early family planning and collaboration between neurology and gynecology, stating that while well-planned pregnancies are ideal, ART is a safe and effective option for those with MS.
Article Synopsis
- The concept of adequacy in peritoneal dialysis has evolved from focusing mainly on specific goals like solute clearance to prioritizing the overall quality of life for patients.
- This document aims to provide updated recommendations regarding peritoneal dialysis adequacy, covering key areas such as residual kidney function and different types of dialysis methods.
- A systematic approach (GRADE) was employed to highlight the quality of evidence for recommendations, and the document references a recent guide by experts from the International Society of Peritoneal Dialysis for additional support.
Purpose: Rapid, reliable identification of mycobacteria from positive cultures is essential for patient management, particularly for the differential diagnosis of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacteria (NTM) species. The aim of the present study was to evaluate a new "In-Vitro-Diagnostic"-certified PCR kit, FluoroType®-Mycobacteria VER 1.0 (Hain Lifescience GmbH) for NTM and MTBC identification from cultures.
View Article and Find Full Text PDFNo consensus exists about the techniques to use for microbiological diagnosis of bone and joint infections (BJIs). The objective herein was to define an algorithm to optimize BJI diagnosis in adults using various bacteriological methods on synovial fluid samples. This prospective multi-center study included 423 synovial fluids collected from adult patients with suspected BJIs.
View Article and Find Full Text PDFLarge transcellular pores elicited by bacterial mono-ADP-ribosyltransferase (mART) exotoxins inhibiting the small RhoA GTPase compromise the endothelial barrier. Recent advances in biophysical modeling point toward membrane tension and bending rigidity as the minimal set of mechanical parameters determining the nucleation and maximal size of transendothelial cell macroaperture (TEM) tunnels induced by bacterial RhoA-targeting mART exotoxins. We report that cellular depletion of caveolin-1, the membrane-embedded building block of caveolae, and depletion of cavin-1, the master regulator of caveolae invaginations, increase the number of TEMs per cell.
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