Tumor invasion optimization by mesenchymal-amoeboid heterogeneity.

Metastasizing tumor cells migrate through the surrounding tissue and extracellular matrix toward the blood vessels, in order to colonize distant organs. They typically move in a dense environment, filled with other cells. In this work we study cooperative effects between neighboring cells of different types, migrating in a maze-like environment with directional cue.

Effect of preoperative antibiotic prophylaxis on surgical site infections complicating cardiac surgery.

Objective: To evaluate the effect of an optimized policy for antibiotic prophylaxis on surgical site infection (SSI) rates in cardiac surgery.

Design: Prospective cohort study.

Setting: Tertiary medical center in Israel.

Decision-support information system to manage mass casualty incidents at a level 1 trauma center.

Mass casualty incidents are probably the greatest challenge to a hospital. When such an event occurs, hospitals are required to instantly switch from their routine activity to conditions of great uncertainty and confront needs that exceed resources. We describe an information system that was uniquely designed for managing mass casualty events.

Moral dilemmas faced by hospitals in time of war: the Rambam Medical Center during the second Lebanon war.

Rambam Medical Center, the only tertiary care center and largest hospital in northern Israel, was subjected to continuous rocket attacks in 2006. This extreme situation posed serious and unprecedented ethical dilemmas to the hospital management. An ambiguous situation arose that required routine patient care in a tertiary modern hospital together with implementation of emergency measures while under direct fire.