Publications by authors named "Y Banz"
Background: The human microbiome is crucial in regulating intestinal and systemic functions. While its role in cardiovascular disease is better understood, the link between intestinal microbiota and valvular heart diseases (VHD) remains largely unexplored.
Methods: Peer-reviewed studies on human, animal or cell models analysing gut microbiota profiles published up to April 2024 were included.
Article Synopsis
- Researchers aimed to improve a porcine model used for vascularized composite allotransplantation (VCA) by reducing its bulk and including critical vascularized lymph nodes.
- The study involved harvesting and analyzing porcine flaps using both conventional and modified techniques, with results showing a significant reduction in flap weight and muscle/bone ratio in the modified group.
- The findings indicate that the modified model maintains vascularization while providing a more suitable platform for studying immunological responses in transplant research, suggesting its potential for broader experimental applications.
Introduction: The introduction of CAR-T cell treatment for relapsed/refractory (r/r) mantle cell lymphoma improved survival rates of these patients. Along with its introduction in clinical routine, long-term events after CAR-T cell treatment are increasingly emerging.
Case Presentation: We report the case of a patient developing acute erythroid leukemia with biallelic inactivation occurring 26 months after CAR-T therapy with brexucabtagene autoleucel (brexu-cel) for r/r mantle cell lymphoma.
Article Synopsis
- This study explores the immune rejection of cartilage in vascularized composite allotransplantation (VCA), which is vital for restoring motor function in joint transplants.
- Using a swine model, researchers analyzed tissue samples from grafts that experienced severe skin rejection and found evidence of immune attacks on cartilage but with less severity than skin and muscle.
- The findings indicate that cartilage is not immune from rejection in VCA, showing significant immune response activity, including markers of cell death, although it endures milder inflammation compared to other tissues.