The pervasive model for a solvated, ion-filled nanopore is often a resistor in parallel with a capacitor. For conical nanopore geometries, here we propose the inclusion of a Warburg-like element, which is necessary to explain otherwise anomalous observations such as negative capacitance and low-pass filtering of translocation events (we term this phenomenon as Warburg filtering). The negative capacitance observed here has long equilibration times and memory (that is, mem-capacitance) at negative voltages.
View Article and Find Full Text PDFBackground: Limited information is available on electrolyte abnormalities in cats with chronic inflammatory enteropathy (CIE).
Hypothesis/objectives: Report the prevalence of electrolyte abnormalities in cats with CIE compared to other gastrointestinal disorders, and determine their association with disease and outcome variables in cats with CIE.
Animals: Three hundred twenty-eight client-owned cats from 2 referral hospitals: CIE (132), alimentary small cell lymphoma (29), acute gastroenteritis (48), and healthy controls (119).
The success of a nanopore experiment relies not only on the quality of the experimental design but also on the performance of the analysis program utilized to decipher the ionic perturbations necessary for understanding the fundamental molecular intricacies. An event extraction framework is developed that leverages parallel computing, efficient memory management, and vectorization, yielding significant performance enhancement. The newly developed abf-ultra-simple function extracts key parameters from the header critical for the operation of open-seek-read-close data loading architecture running on multiple cores.
View Article and Find Full Text PDFAn electronic nose (E-nose) is a technology fundamentally inspired by the human nose, designed to detect, recognize, and differentiate specific odors or volatile components in complex and chaotic environments. Comprising an array of sensors with meticulously designed nanostructured architectures, E-noses translate the chemical information captured by these sensors into useful metrics using complex pattern recognition algorithms. E-noses can significantly enhance the quality of life by offering preventive point-of-care devices for medical diagnostics through breath analysis, and by monitoring and tracking hazardous and toxic gases in the environment.
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