Publications by authors named "Y Bailly"
The embryonic development of the pig comprises a long in utero pre- and peri-implantation development, which dramatically differs from mice and humans. During this peri-implantation period, a complex series of paracrine signals establishes an intimate dialogue between the embryo and the uterus. To better understand the biology of the pig blastocyst during this period, we generated a large dataset of single-cell RNAseq from early and hatched blastocysts, spheroid and ovoid conceptus and proteomic datasets from corresponding uterine fluids.
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- Yersinia enterocolitica is a key cause of foodborne illnesses, with the BT4/O:3 strain being the most common in humans.
- Pigs are the primary carriers, and this study explored how the bacteria infects them through oral and nasal routes, delineating three stages of colonization.
- The research found that while the bacteria could persist for up to 56 days, notable genetic changes occurred in some strains, suggesting variations in their ability to cause human infections.
Glioblastoma (GBM) is the most common primary brain tumor in adults. Despite conventional treatment, consisting of a chirurgical resection followed by concomitant radio-chemotherapy, the 5-year survival rate is less than 5%. Few risk factors are clearly identified, but women are 1.
View Article and Find Full Text PDFStatistical Analysis of Absenteeism in a University Hospital Center between 2007 and 2019.
Int J Environ Res Public Health
October 2022
Objectives: To estimate the evolution of compressible absenteeism in a hospital center and identify the professional and sociodemographic factors that influence absenteeism.
Method: All hospital center employees have been included over a period of twelve consecutive years (2007 to 2019). Compressible absences and occupational and sociodemographic factors were analyzed using Occupational Health data.
Background: Epidemiological emerging evidence shows that human exposure to some nanosized materials present in the environment would contribute to the onset and/or progression of Alzheimer's disease (AD). The cellular and molecular mechanisms whereby nanoparticles would exert some adverse effects towards neurons and take part in AD pathology are nevertheless unknown.
Results: Here, we provide the prime evidence that titanium dioxide (TiO) and carbon black (CB) nanoparticles (NPs) bind the cellular form of the prion protein (PrP), a plasma membrane protein well known for its implication in prion diseases and prion-like diseases, such as AD.