Myceliophthora thermophila as promising fungal cell factories for industrial bioproduction: From rational design to industrial applications.

Myceliophthora thermophila stands out as a prominent fungal cell factory, garnering growing interest due to its distinctive traits advantageous. Currently, M. thermophila has been developed as an efficient cell factory, producing a variety of products from various raw materials.

Ten simple rules for good model-sharing practices.

Computational models are complex scientific constructs that have become essential for us to better understand the world. Many models are valuable for peers within and beyond disciplinary boundaries. However, there are no widely agreed-upon standards for sharing models.

deep-AMPpred: A Deep Learning Method for Identifying Antimicrobial Peptides and Their Functional Activities.

Antimicrobial peptides (AMPs) are small peptides that play an important role in disease defense. As the problem of pathogen resistance caused by the misuse of antibiotics intensifies, the identification of AMPs as alternatives to antibiotics has become a hot topic. Accurately identifying AMPs using computational methods has been a key issue in the field of bioinformatics in recent years.

Carbon Storage Response to Land Use/Land Cover Changes and SSP-RCP Scenarios Simulation: A Case Study in Yunnan Province, China.

Changes in terrestrial ecosystem carbon storage (CS) affect the global carbon cycle, thereby influencing global climate change. Land use/land cover (LULC) shifts are key drivers of CS changes, making it crucial to predict their impact on CS for low-carbon development. Most studies model future LULC by adjusting change proportions, leading to overly subjective simulations.

Gengnianchun Against HO-Induced Oxidative Damage in KGN Cells via miR-548m/FOXO3 Signaling.

Gengnianchun (GNC) is a traditional remedy used for diminished ovarian reserve, but its underlying mechanisms remain unclear. This study aimed to explore these mechanisms in human granulosa-like cancer (KGN) cells pretreated with medicated rat serum (MRS) before HO exposure. MRS pretreatment significantly alleviated HO-induced cell damage, including improvements in cell viability, superoxide dismutase and GSH-Px activities, and Bcl-2 expression.