Revised dietary exposure assessment of the food enzyme thrombin from cattle (bovines) and pig's blood.

The food enzyme thrombin (EC 3.4.21.

Understanding Noninferiority Trials: What Stroke Specialists Should Know.

Noninferiority trials aim to prove that the efficacy, defined in terms of a key clinical outcome, of a new treatment is not meaningfully worse than that of an established active control. Noninferiority trials are important when other aspects of care can be improved, such as convenience, toxicity, costs, and safety (nonefficacy benefits). While the motivation for a noninferiority trial is straightforward, the design, execution, and interpretation of these trials is not a trivial task.

High-Risk Embolic Sources on Cardiac Computed Tomography in Patients With Acute Ischemic Stroke: A Case-Control Study.

Background: Cardiac computed tomography (CT) is increasingly used to search for cardioembolic sources of acute ischemic stroke (AIS). We assessed the association between high-risk cardioembolic sources on cardiac CT and AIS.

Methods: We performed a case-control study using data from a prospective cohort including consecutive adult patients with suspected stroke who underwent cardiac CT acquired during the initial stroke imaging protocol between 2018 and 2020.

Revised dietary exposure assessment of the food enzyme triacylglycerol lipase from the genetically modified strain NZYM-AL.

The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.

Safety evaluation of the food enzyme β-fructofuranosidase from the non-genetically modified strain CNCM I-3399.

The food enzyme β-fructofuranosidase (β-d-fructofuranoside fructohydrolase; EC 3.2.1.