Preoperative NSAID Use is Associated With a Small But Statistically Significant Increase in Blood Drainage in TLIF Procedures.

Study Design: Retrospective analysis of retrospectively collected data.

Objective: To determine the effects of preoperative nonsteroidal anti-inflammatory drug (NSAID) use on estimated blood loss (EBL) and postoperative drain output in TLIF procedures.

Summary Of Background Data: Current standards of care recommend patients prescribed NSAIDs for chronic lower back pain discontinue NSAIDs at least 1 week before spine fusion surgery.

Climate and malaria: modeling non-linear dynamics in the Nordic countries during the 18th and 19th centuries.

Aims: Until the late 19th century, malaria was endemic in most of Europe including in the Nordic countries. In Denmark, Finland, and Sweden, the fluctuations in malaria cases and malaria-attributed deaths are known to have been associated with weather conditions, in particular with mean summer temperature variations. However, to what extent other environmental factors could have increased or decreased the risk of malaria has not previously been evaluated using historical records.

Proteomic Analyses of Clots Identify Stroke Etiologies in Patients Undergoing Endovascular Therapy.

Aims: This study aimed to investigate the correlation between clot composition and stroke mechanisms in patients undergoing endovascular therapy (EVT), using proteomic analysis.

Methods: This study included 35 patients with ischemic stroke (cardioembolism [CE], n = 17; large artery atherosclerosis [LAA], n = 6; cancer-related [CR], n = 4; and undetermined (UD) cause, n = 8) who underwent EVT. Retrieved clots were proteomically analyzed to identify differentially expressed proteins associated with the three stroke mechanisms and to develop the machine learning model.

Proteinuria Is Associated With an Increased Risk of Sudden Cardiac Arrest in the Young Population.

Background: Proteinuria is a risk factor for cardiovascular events, but its prognostic value for sudden cardiac arrest (SCA) in young individuals remains unproven. We aimed to evaluate whether proteinuria in young people is associated with an increased risk of SCA.

Methods And Results: Individuals aged between 20 and 39 years who underwent health screening between 2009 and 2012 in South Korea were included (n=6 891 400).

Role of Ethylene Diamine Tetraacetate as an Additive in Electrolyte on Intermediate Stabilization in Electrochemical CO2 Reduction.

Although an electrochemical CO2 reduction reaction (ECO2RR) can provide an ideal route to produce CH4, its selectivity is significantly hindered due to kinetically complex steps. To improve CH4 selectivity, this study focuses on microenvironmental engineering using an additive of ethylene diamine tetraacetate (EDTA) in electrolyte. EDTA interacts with the Cu catalyst, altering its electronic structure and promoting CO2 activation, in addition, it forms additional hydrogen bonding with key intermediates of *CO and *CHO leading to their stabilization.