The psychometric properties of the EQ-HWB and EQ-HWB-S in patients with breast cancer: a comparative analysis with EQ-5D-5L, FACT-8D and SWEMWBS.

Objectives: The EQ Health and Well Being is a new generic measure that captures constructs beyond health-related quality of life, with a 25-item long form (EQ-HWB) and a shorter 9-item version (EQ-HWB-S). This study aims to assess the psychometric performance of both versions in breast cancer, which is the most prevalent cancer globally, and compare them to other instruments.

Methods: A longitudinal survey in Indonesia (2023-24) with 300 female patients used the EQ-HWB, EQ-5D-5L, Functional Assessment of Cancer Therapy-General (FACT-G, from which FACT-8D was derived), Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS, from which SWEMWBS was derived).

Effect of Androgen receptors in Triple-Negative Breast Cancer Given Neoadjuvant Therapy: A Systematic Review and Meta-Analysis.

Objective: Triple-negative breast cancer (TNBC) is a type of breast cancer that does not express the estrogen receptor (ER), the progesterone receptor (PR), or the human epidermal growth factor receptor 2 (HER2). TNBC has limited treatment targets, including the androgen receptor (AR). However, the therapeutic strategies-based AR expression in TNBC remains uncertain.

Causes of mortality following PCI: the University of New Mexico hospital experience.

Background: Mortality after percutaneous coronary intervention (PCI) remains a problem. Clinical databases such as the American College of Cardiology National Cardiovascular Data CathPCI Registry do not contain enough information to determine the specific cause of death after PCI, and thus are not able to identify opportunities for improvement (OFIs) that might have prevented the death of specific patients. We reviewed cases of death after coronary intervention to identify specific OFIs.

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

The intricate dynamics of Hes expression across diverse cell types in the developing vertebrate embryonic tail have remained elusive. To address this, we have developed an endogenously tagged Hes1-Achilles mouse line, enabling precise quantification of dynamics at the single-cell resolution across various tissues. Our findings reveal striking disparities in Hes1 dynamics between presomitic mesoderm (PSM) and preneural tube (pre-NT) cells.