Publications by authors named "Y Azaz"

In a longitudinal, population based study, overnight temperature recordings were made in the bedrooms of 152 babies aged 3-18 weeks and the insulation provided by their bedclothing was assessed. Outdoor temperatures for the study nights were also available. Parents applied more insulation on colder nights with lower bedroom temperatures than on warmer nights (mean 8.

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In summary, there is evidence that developmental changes in respiratory control and in thermoregulation have effects upon each other. Theoretically, such effects could give rise to failure of the respiratory system and there is some circumstantial evidence to support the concept that on occasions such interactions may be of importance in sudden unexpected death in infancy. Future research in this area should focus on the nature of the interactions between thermoregulation and respiration, and on the effects of infection and infection-related mediators on those interactions.

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Over the first three months of life the infant's metabolic rate rises, which, together with the rise in ratio of mass to surface area, means that the net heat loss per unit surface area is 50% higher in a 3 month old infant than in a neonate. This, together with the thicker layer of subcutaneous fat and more effective peripheral vasomotor response to cold in a 3 month old infant, means that thermal balance is shifted in favour of heat conservation. The head is the site of 40% of heat production and of up to 85% of heat loss in an infant in bed: covers rising up over the head could therefore result in acute thermal imbalance with a rise in brain temperature not necessarily accompanied by a rise in body temperature.

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We have investigated the effect of changing environmental temperature on metabolic rate, sleep state, and water loss in a longitudinal study of 22 lightly clothed babies from 2 d to 3 mo of age. Studies were performed in a modified barometric plethysmograph while recording sleep state, oxygen consumption, and skin and axillary temperatures. Oxygen consumption was higher in rapid eye movement sleep than in quiet sleep at all ages and varied widely between infants at each temperature.

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Objective: To determine the relation between sleeping position and quantity of bedding and the risk of sudden unexpected infant death.

Design: A study of all infants dying suddenly and unexpectedly and of two controls matched for age and date with each index case. The parents of control infants were interviewed within 72 hours of the index infant's death.

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