Japan Diabetes Complications Study: Revisiting one of the first large-scale clinical studies in East Asians with diabetes.

This review highlights the significance of the Japan Diabetes Complications Study (JDCS), one of the earliest large-scale studies of people with type 2 diabetes outside Europe and the United States, in understanding type 2 diabetes mellitus among East Asian populations, particularly in Japan. Historically, large-scale clinical studies on type 2 diabetes mellitus have predominantly focused on Western populations, despite East Asians comprising the largest proportion of diabetic patients globally. The JDCS, which was initiated in 1996, enrolled 2,033 Japanese type 2 diabetes mellitus patients.

First in Japan: Training Curriculum for Perianesthesia Nurses and Their Clinical Practice.

Problem Definition: Japan is dealing with a superageing society found nowhere else in the world. This problem is provoking other complex issues such as aggravation of patients' condition, and a shortage of anesthesiologists leading to overwork.

Strategies To Address The Problem: As a solution, our hospital established the PeriAnesthesia Nurse (PAN) for the first time in Japan.

Analgesic Efficacy of a Combination of Fentanyl and a Japanese Herbal Medicine "" in Rats with Acute Inflammatory Pain.

Fentanyl can induce acute opioid tolerance and postoperative hyperalgesia when administered at a single high dose; thus, this study examined the analgesic efficacy of a combination of fentanyl and (YKS). Rats were divided into control, formalin-injected (FOR), YKS-treated+FOR (YKS), fentanyl-treated+FOR (FEN), and YKS+FEN+FOR (YKS+FEN) groups. Acute pain was induced via subcutaneous injection of formalin into the paw.

Silver in the Center Enhances Room-Temperature Phosphorescence of a Platinum Sub-nanocluster by 18 Times.

There has been controversy surrounding the roles of the metal core (metal-metal interaction) and the shell (metal-ligand interaction) in photoluminescence of ligand-protected metal nanoclusters. We have discovered aggregation-induced room-temperature phosphorescence of a platinum-thiolate complex and its silver ion inclusion complex (a silver-doped platinum sub-nanocluster). The inclusion of silver ion boosted the photoluminescent quantum yield by 18 times.

Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes.

The aim of this study was to investigate the association between protein intake and mortality risk in patients with type 2 diabetes. We analyzed a pooled data of 2494 diabetic patients from two prospective longitudinal studies. Nutritional intake was assessed using a Food Frequency Questionnaire at baseline.