Mushrooms are valued for their culinary and medicinal benefits, containing bioactive compounds like polysaccharides, terpenoids, phenolics, lectins, and ergosterols. This review aims to encourage research on by summarizing its chemistry, health benefits, pharmacology, and potential therapeutic applications. Molecules from offer anti-diabetic, antioxidant, anti-tumor, hepatoprotective, and anti-bacterial effects.
View Article and Find Full Text PDFItaconate, an abundant metabolite produced by macrophages upon interferon-γ stimulation, possesses both antibacterial and immunomodulatory properties. Despite its crucial role in immunity and antimicrobial control, its mechanism of action and dissimilation are poorly understood. Here, we demonstrate that infection of mice with increases itaconate levels in lung tissues.
View Article and Find Full Text PDFThe problem at hand is the significant global health challenge posed by children's diseases, where timely and accurate diagnosis is crucial for effective treatment and management. Conventional diagnosis techniques are typical, use tedious processes and generate inaccurate results since they are executed by human beings and cause delays in treatment that can be fatal. Considering these and other shortcomings there exists a need to have more efficient and accurate solutions based on artificial intelligence.
View Article and Find Full Text PDFUsing angle-resolved photoemission spectroscopy (ARPES) and density functional theory (DFT), an experimental and theoretical study of changes in the electronic structure (dispersion dependencies) and corresponding modification of the energy band gap at the Dirac point (DP) for topological insulator (TI) [Formula: see text] have been carried out with gradual replacement of magnetic Mn atoms by non-magnetic Ge atoms when concentration of the latter was varied from 10% to 75%. It was shown that when Ge concentration increases, the bulk band gap decreases and reaches zero plateau in the concentration range of 45-60% while trivial surface states (TrSS) are present and exhibit an energy splitting of 100 and 70 meV in different types of measurements. It was also shown that TSS disappear from the measured band dispersions at a Ge concentration of about 40%.
View Article and Find Full Text PDFThis study presents an experimental investigation of the quasi-static and dynamic behavior of a quasi-isotropic carbon-fiber-reinforced composite subjected to in-plane compressive loading. The experiments were performed at strain rates ranging from 4×10-5 to ∼1200 s-1 to quantifythe strain-rate-dependent response, failure propagation, and damage morphology using advanced camera systems. Fiber bridging, kink band formation, dominance of interlaminar failure, and inter-fiber failure fracture planes are evidenced through post-mortem analysis.
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