Publications by authors named "Y Aida"

The proviral load (PVL) of the bovine leukemia virus (BLV) is a useful index for estimating disease progression and transmission risk. Real-time quantitative PCR techniques are widely used for PVL quantification. We previously developed a dual-target detection method, the "Liquid Dual-CoCoMo assay", that uses the coordination of common motif (CoCoMo) degenerate primers.

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Ventriculoperitoneal shunt malfunction is a common complication in patients with lifelong hydrocephalus. We present a case of a 40-year-old man who successfully underwent endoscopic third ventriculostomy (ETV) for shunt malfunction following neonatal meningitis. Despite long-term shunt dependency and an infectious etiology, ETV effectively managed his hydrocephalus, probably due to aqueductal stenosis and preserved cerebrospinal fluid absorption.

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Article Synopsis
  • Primary mediastinal germ cell tumor (PMGCT), particularly choriocarcinoma, has a poor prognosis and is treated with BEP therapy, which can lead to complications like acute respiratory distress syndrome (ARDS).
  • A 38-year-old woman diagnosed with advanced primary mediastinal choriocarcinoma underwent BEP therapy, resulting in a significant reduction of hCG levels.
  • To minimize the risk of ARDS, she switched to VIP therapy and successfully underwent surgical resection, remaining disease-free for 16 months post-surgery.
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Coenzyme Q10 is an essential lipid in the mitochondrial electron transport system and an important antioxidant. It declines with age and in various diseases, there is a need for a method to compensate for the decrease in coenzyme Q10. Resveratrol, a well-known anti-aging compound, has been shown to undergo metabolism to coenzyme Q10's benzene ring moiety in cells.

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Article Synopsis
  • * Incretin hormones increase MafA expression through the CREB-CRTC2 pathway, but the exact mechanisms of this regulation remain unclear.
  • * Research using ChIP-seq data shows that CREB and NeuroD1 bind to MafA's regulatory regions, with specific elements necessary for transcriptional activation, aiding in understanding how CREB controls MafA and other β-cell genes.
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