Assessing the role of Berberine as an inhibitor of advanced glycation end products (AGEs) formation using in vitro and molecular interaction studies.

Glycation and aggregation of proteins have garnered more interest in recent years. Glycation leads to the formation of protein aggregates and advanced glycation ends (AGEs) that play crucial roles within several pathological conditions. The objective of our study is to gain a deeper understanding of the formation of AGEs and aggregates of human serum albumin (HSA) in the presence of methylglyoxal and the protective effects of the phytochemical berberine.

Small bowel obstruction caused by transmesenteric hernia in a patient with complex medical history: a case report.

This case report presents a rare instance of small bowel obstruction due to a transmesenteric hernia in a 47-year-old male with a complex medical history. The patient presented with acute abdominal pain, constipation, and urinary retention. Diagnostic laparoscopy revealed bowel ischemia, and open laparotomy confirmed a transmesenteric hernia with necrotic small bowel requiring resection.

In-Hospital Outcomes and 30-Day Readmission Rate After Transcatheter and Surgical Aortic Valve Replacement in Liver Cirrhosis: A Contemporary Propensity-Matched Analysis.

Background: Liver cirrhosis is not included in surgical risk prediction models despite being a significant risk factor associated with high periprocedural morbidity and mortality in patients undergoing cardiac surgery. Limited contemporary data exists assessing the outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with cirrhosis.

Methods: Patients with cirrhosis who underwent TAVR or SAVR were identified from the Nationwide Readmissions Database.

Long-term outcomes with medical therapy, transcatheter repair, or surgery for isolated tricuspid regurgitation: a systematic review and network meta-analysis.

Background: Several transcatheter tricuspid valve (TV) repair devices for tricuspid regurgitation (TR) have emerged. However, few studies have compared transcatheter TV repair with medical therapy (MT) alone or isolated TV surgery.

Methods: PubMed and EMBASE were searched in February 2024.

Panoramic Assessment of Mental Foramen Location in Adult Patients in Riyadh, Saudi Arabia: A Retrospective Cross-Sectional Study.

Objectives: This retrospective cross-sectional study aimed to determine the localization of the mental foramen in a Saudi population using panoramic radiographs, identify the most common vertical and horizontal positions, assess bilateral symmetry, and analyze variations based on age and gender.

Methods: Digital panoramic radiographs of 504 patients, aged 18-58 years, were analyzed. The variables assessed included age group, gender, vertical position (Zones A, B, and C), horizontal position (Zones 1-6), and symmetry (present/absent) of the mental foramen location bilaterally.