Publications by authors named "Y Afassinou"

Article Synopsis
  • A study found that Afro-Caribbeans have a lower mortality rate from coronary artery disease (CAD) and better lipid profiles compared to Europeans.
  • Researchers analyzed 705 Afro-Caribbeans, genotyping them for 13 lipid-related variants while calculating polygenic risk scores for LDL, HDL, and triglycerides.
  • The study revealed that higher LDL-PRS was linked to elevated LDL levels and an increased risk of CAD, while HDL-PRS and TG-PRS showed no significant association with CAD.
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Cognitive decline and comorbid conditions commonly co-occur, and these conditions can affect cognitive health. We aimed to estimate the prevalence of cognitive impairment (CI) according to weight status and to evaluate the associations between CI, weight status and comorbid conditions in adults of 55 years and older. The Abbreviated Mental Test Score (AMTS) was used.

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Background: Our study aimed to describe the clinical, paraclinical, therapeutic and outcomes of patients with venous thromboembolic event (VTE) associated with cancer in the context of limited resources.

Materials And Methods: This was a descriptive cross-sectional study over a period of six years from March 1, 2016 to March 31, 2022, in the cardiology department and the oncology unit of the Sylvanus Olympio Teaching Hospital of Lome. Our study examined medical records of patients who were at least 18 years old and had venous thromboembolic disease and cancer that was histologically confirmed.

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Article Synopsis
  • A study in Guadeloupe aimed to determine the prevalence of metabolic syndrome (MetS) among Afro-Caribbean adults without diabetes or cardiovascular issues, using the NCEP ATP III definition.
  • Out of 1011 participants (mostly women), the overall MetS prevalence was 17.9%, notably higher in women (21.1%) than men (10.8%), and increased with age, especially in women.
  • The findings indicated that adults aged 60 and older had significantly higher odds of hypertension, abdominal obesity, and high fasting blood glucose levels, highlighting the need for preventive measures against MetS, particularly for older adults and women.
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Background Data in the literature on acute coronary syndrome in sub-Saharan Africa are scarce. Methods and Results We conducted a systematic review of the MEDLINE (PubMed) database of observational studies of acute coronary syndrome in sub-Saharan Africa from January 1, 2010 to June 30, 2020. Acute coronary syndrome was defined according to current definitions.

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