Publications by authors named "Y A W Hartman"
Article Synopsis
- Chronic ischemic limb disease can lead to amputations, making it a major medical concern, and smooth muscle cells (SMCs) play a key role in various cardiovascular issues.
- Researchers tested two new methods for converting human induced-pluripotent stem cells (hiPSCs) into SMCs, comparing traditional 2D techniques with innovative 3D followed by 2D approaches.
- Results showed that the 3D + 2D protocols significantly increased the number of hiPSC-SMCs produced and confirmed their effectiveness through various in-vitro and in-vivo experiments, indicating a promising avenue for treating ischemic limb conditions.
Effects of a combined exercise and dietary intervention on clinical outcomes in patients with ovarian cancer: the Physical Activity and Dietary intervention in OVArian cancer (PADOVA) randomized controlled trial.
Int J Gynecol Cancer
September 2024
Objective: Chemotherapy treatment modifications can impact survival in patients with ovarian cancer, particularly when the relative dose intensity falls below 85%. Exercise and dietary interventions may benefit treatment tolerability. This study aimed to explore the effects of a combined exercise and dietary intervention on secondary outcomes of the Physical Activity and Dietary intervention in OVArian cancer (PADOVA) trial, specifically relative dose intensity and progression-free survival.
View Article and Find Full Text PDFPurpose: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has continually increased during the past several decades. Using transoral robotic surgery (TORS) significantly improves functional outcomes relative to open surgery for OPSCC. However, TORS limits tactile feedback, which is often the most important element of cancer surgery.
View Article and Find Full Text PDFBackground: Guidelines recommend to include exercise and dietary advice in standard care for patients with cancer, based on evidence primarily derived from patients with breast cancer. Its applicability to patients with ovarian cancer is uncertain due to differences in patient characteristics and treatments. The PADOVA trial examined the effectiveness of a combined exercise and dietary intervention on fat-free mass (FFM), physical functioning, and fatigue.
View Article and Find Full Text PDFObjective: To study physical activity and dietary intake among patients with ovarian cancer and to examine which demographic, clinical, and sociocognitive determinants are associated with these behaviours.
Methods: This cross-sectional study included 139 patients with ovarian cancer scheduled for (neo)adjuvant chemotherapy. Physical activity was measured with the Physical Activity Scale for the Elderly questionnaire (PASE).