Publications by authors named "Y A Shapira"

Article Synopsis
  • This study explores the outcomes and management of pediatric auditory brainstem implantation (ABI) for children with severe inner ear malformations, aiming to unify clinical practices and address current challenges.
  • A systematic review of relevant findings from the Third International Pediatric ABI Symposium analyzed data from multiple countries, highlighting trends in auditory outcomes, surgical approaches, and rehabilitation strategies.
  • Key conclusions emphasize the need for standardized guidelines and improved collaboration among healthcare professionals to enhance patient outcomes and guide future research in this specialized field.
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Article Synopsis
  • The study aimed to assess the effectiveness of subconjunctival tranexamic acid (TXA) in reducing bleeding, shortening surgery time, and enhancing recovery in pterygium surgery through a double-blind, randomized controlled trial involving 50 patients.
  • Results showed no significant differences between the TXA group and the saline control group in terms of surgery duration, intraoperative bleeding, or postoperative visual acuity, with both groups faring similarly in all main outcome measures.
  • Although the use of TXA was deemed safe with no adverse effects, the findings suggest that it does not provide substantial benefits in improving surgical outcomes for pterygium surgery, indicating a need for further research on alternative treatments or surgical techniques.
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Article Synopsis
  • Conjunctival melanoma, a rare type of ocular melanoma, has some genetic similarities to both skin and mucosal melanoma and presents unique treatment challenges when advanced or metastatic.
  • The FDA recently approved the combination treatment Nivolumab/relatlimab (Opdualag) for metastatic melanoma, showing improved survival rates in earlier treatment stages without significant safety concerns, but its effectiveness in conjunctival melanoma is still unknown.
  • In a case study, an 87-year-old woman with advanced conjunctival melanoma showed a near-complete clinical response after just one cycle of Opdualag, although treatment was limited to four cycles due to her worsening dementia.
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Background: Foreign bodies that migrate into the heart may include medical devices dislodged from their original location or, rarely, external particles (shrapnel and other foreign bodies) that penetrate the vein, remain intraluminal, and migrate via the venous blood flow to the right heart. Most reported entry sites of these external foreign bodies were in the torso, thigh, or neck; none of them penetrated through a distal extremity of the body. We report a case where shrapnel was found in the right ventricle (RV) following penetrating injury to the hand.

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Despite diagnostic and therapeutic advances, infective endocarditis (IE) is still associated with high mortality rates. Currently, there are no good prognostic tools for the risk assessment of patients with IE. The CHADS-VASc score, used to estimate the risk of ischemic stroke in patients with non-valvular atrial fibrillation (AF), has been shown to be a powerful predictor of stroke and death in patients without known AF associated with other cardiovascular conditions.

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