Publications by authors named "Y A Gul"
Pharmacological function of melanocortin-3 receptor in goldfish (Carassius auratus).
Gen Comp Endocrinol
January 2025
The melanocortin-3 receptor (MC3R) was recognized for its critical role in energy metabolism and inflammatory responses in mammals; however, its functions in fish remain poorly understood. This study characterized the mc3r gene in goldfish, investigating its sequence, tissue distribution, and pharmacological responses. The coding sequence of goldfish mc3r was 975 bp, translating to a 325-amino-acid protein typical of G protein-coupled receptors, with notable conservation across cyprinids.
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- Green synthesis of Calcium oxide nanoparticles (CaO NPs) using Mulberry leaf extract offers an eco-friendly alternative to traditional methods that are costly and harmful for creating nanocomposites.
- The study finds that CaO NPs can effectively remove 98.2% of Rhodamine B dye from solution under optimized conditions: 80 ppm concentration, 343 K temperature, 60 minutes contact time, and pH 7 using just 0.4 g of the adsorbent.
- Various adsorption and kinetic models, such as Freundlich and pseudo 2nd order, are utilized to analyze and explain the adsorption process, highlighting the potential of CaO NPs for treating industrial wastewater efficiently.
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- ICF syndrome is a rare, autosomal recessive disease linked to mutations in specific genes (DNMT3B, ZBTB24, CDCA7, HELLS) that lead to immune deficiencies and facial anomalies.
- This study examined the expression of transcription factors and cytokines in various helper T cell subsets from ICF patients and found significant reductions in these factors compared to healthy controls.
- It also identified a novel mutation in the ZBTB24 gene related to ICF2 syndrome, marking the first molecular investigation of T cell subsets in ICF syndrome.
Background: Anemia in females of the reproductive age group is an area of concern globally, but its prevalence is high in developing countries. Dietary habits and lifestyle impact the hematological parameters. It is important to evaluate the impact of tea drinking on hematological parameters in females of the reproductive age group.
View Article and Find Full Text PDFNanoplastics (NPs) have been commonly detected in aquatic ecosystems, and their negative effects on aquatic organisms have raised concerns in the scientific community and general public. The acute toxicity, neurotoxicity, and metabolic toxicity induced by NPs on fishes have been reported by many studies, although less attention has been focused on how mother exposed to NPs affected their offspring in aquatic organisms. Here, female zebrafish (F0) were exposed to 0, 200 and 2000 μg/L polystyrene nanoplastics (PS-NPs) for 42 d, with their offspring (F1) reared in clear water until sexual maturity.
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