Low intensity focused ultrasound: a new prospect for the treatment of Parkinson's disease.

As a chronic and progressive neurodegenerative disease, Parkinson's disease (PD) still lacks effective and safe targeted drug therapy. Low-intensity focused ultrasound (LIFU), a new method to stimulate the brain and open the blood-brain barrier (BBB), has been widely concerned by PD researchers due to its non-invasive characteristics. PubMed was searched for the past 10 years using the terms 'focused ultrasound', 'transcranial ultrasound', 'pulse ultrasound', and 'Parkinson's disease'.

Phytoremediation of Cd and Pb interactive polluted soils by switchgrass ( L.).

Using phytoremediation as an efficient technique to remove heavy metals from contaminated soils is a current research hotspot. This study used an orthogonal matrix experimental design with three factors (Cd, Pb, and pH) and five levels (Cd at 9.45, 30, 60, 90, and 110.

Optimizing irrigation and nitrogen fertilization for seed yield in western wheatgrass [Pascopyrum smithii (Rydb.) Á. Löve] using a large multi-factorial field design.

It is crucial for agricultural production to identify the trigger that switches plants from vegetative to reproductive growth. Agricultural sustainability in semiarid regions is challenged by nitrogen (N) fertilizer overuse, inadequate soil water, and heavy carbon emissions. Previous studies focused on the short-term effects of a single application of N and water but have not investigated the long-term effects of different irrigation and N fertilizer regimens on crop yields and yield components.

Effects of ultrasonication on increased germination and improved seedling growth of aged grass seeds of tall fescue and Russian wildrye.

The effects of ultrasonic treatments on the germination and seedling growth of aged tall fescue (Festuca arundinacea) and Russian wild rye (Psathyrostaehys juncea Nevski) seeds were determined using orthogonal matrix experimental design with four ultrasonic factors. The multivariate analysis of variance detected significant differences and coupling effects of the pair-wise factors. The activities of Superoxide Dismutase (SOD) and Peroxidase (POD) and the Malondialdehyde (MDA) content were affected.

Ras activation induces expression of Raet1 family NK receptor ligands.

NK cells play a crucial role in innate immunity against tumors. In many human tumors, Ras is chronically active, and tumor cells frequently express ligands for the activating NK cell receptor NKG2D. In this study, we report that Ras activation upregulates the expression of Raet1 protein family members Rae1α and Rae1β in mouse and ULBP1-3 in human cells.