Publications by authors named "Xuzhou Chen"
Background: To explore a novel semi-automatic quantitative method for detecting lid-wiper epitheliopathy (LWE) and analyze its impact on the distribution of corneal epithelial thickness (CET).
Methods: A total of 37 eyes from 37 adults were included in this study. The lid wipers were stained with lissamine green strips, and the stained areas were recorded using a digital slit-lamp biomicroscopy and analyzed using ImageJ software.
Article Synopsis
- Benign prostatic hyperplasia (BPH) is a prevalent condition in older adults, marked by excessive growth of prostate cells, and neferine—an alkaloid with antioxidant and anti-inflammatory properties—shows promise in treating it.
- Neferine administration in a BPH mouse model reduced prostate weight and expression levels of various proteins linked to BPH progression, potentially indicating its effectiveness in managing the disease.
- Additionally, neferine appears to counteract the effects of TGF-β1 on prostate cells, suggesting its role in regulating important signaling pathways that contribute to prostate health, making it a potential candidate for BPH treatment.
Introduction: Prostate cancer is the second-leading cause of cancer death in men. Sinularin is a soft coralsderived natural compound that has anticancer activity in many cancer cells. However, the pharmacological action of sinularin in prostate cancer is unclear.
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