Objective: Involvement of NLR CARD domain containing 4 (NLRC4) in neuroinflammation has been demonstrated. The aim of this study was to ascertain the prognostic role of serum NLRC4 in severe traumatic brain injury (sTBI).
Methods: In this prospective cohort study including 140 sTBI patients and 140 controls, serum NLRC4 levels were quantified.