Modular Assembly of MXene Frameworks for Noninvasive Disease Diagnosis via Urinary Volatiles.

Volatile organic compounds (VOCs) in urine are valuable biomarkers for noninvasive disease diagnosis. Herein, a facile coordination-driven modular assembly strategy is used for developing a library of gas-sensing materials based on porous MXene frameworks (MFs). Taking advantage of modules with diverse composition and tunable structure, our MFs-based library can provide more choices to satisfy gas-sensing demands.

Debonding-On-Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication.

Herein, a multifunctional bilayer wound patch is developed by integrating a debonding-on-demand polymeric tissue adhesive (DDPTA) with an ionic conducting elastomer (ICE). As a skin adhesive layer, the DDPTA is soft and adherent at skin temperature but hard and non-tacky when cooled, so it provides unique temperature-triggered quick adhesion and non-forced detachment from the skin. During use, the dense surface of the DDPTA prevents blood infiltration and reduces unnecessary blood loss with gentle pressing.

Fluorescent pattern recognition of metal ions by nanoparticles of bovine serum albumin as a chemical nose/tongue.

A sensor array mimicking a chemical nose/tongue based on bovine serum albumin nanoparticles (BSANsn) has been developed for the fluorescence pattern recognition of metal ions in biofluids. Three types of BSANsn (BSANs10, BSANs20, and BSANs40) show the same excitation/emission peak at 478/526 nm. According to the differential fluorescence variation, the sensor array shows particular fluorescence response patterns depending upon metal ions.

Electrospun Mussel-derived Silk Fibers.

Background: Though there are many patents on silk, patents on sea silk are rare. Sea silk is one of the most coveted materials in the world, and the technology to make sea silk is at an extremely high risk of extinction. Unlike spider dragline silk and silkworm silk, this natural silk has been forgotten in the academic commune for millennia, though it has many fascinating properties: high strength, remarkable adhesion, extreme lightweight, and others.

Tailor-Made Engineering of Bioinspired Inks for Writing Barcode-like Multifunctional Sensory Electronics.

This letter reports on a novel cost-efficient and multifunctional barcode-like sensors array (BLSA) printed with a conductive bioinspired smart ink. The conductive  ink (P@G ink), which can be further chemically engineered with different organic ligands, was generated via facile one-pot hydrothermal reduction of graphene oxide (GO) in dopamine (DA) as coreductan Usingvarious  chemical derivatives of the P@G inks on a flexible substrate (e.g.

pH-Regulated Optical Performances in Organic/Inorganic Hybrid: A Dual-Mode Sensor Array for Pattern-Recognition-Based Biosensing.

Dual-mode optical assays are becoming more popular and attractive because they would provide robust detailed information in biochemical analysis. We herein unveil a novel dual-mode optical (i.e.

Ratiometric fluorescence monitoring of cerebral Cu based on coumarin-labeled DNA coupled with the Cu-induced oxidation of o-phenylenediamine.

A novel and facile ratiometric fluorescence method for evaluating Cu has been developed based on coumarin-labeled single-stranded DNA (C-ssDNA) coupled with the Cu-induced oxidation of o-phenylenediamine (OPD). By combining the microdialysis technique, the ratiometric fluorescence method has also been successfully exploited to monitor the cerebral Cu in the rat brain, promising new opportunities for studying the cerebral Cu-associated physiological and pathological events.