Systematic coupling and multistage interactive response of the urban land use efficiency and ecological environment quality.

Rapid urbanization and industrialization have greatly contributed to boosting regional economic growth and mitigating the problem of poverty, but blind expansion of cities and towns has not only caused the inefficient use of urban land resources but also caused the deterioration in the urban ecological environment. Within the current context of emphasizing high-quality development, achieving synergy between the efficient use of urban land and ecological environmental protection is an urgent task for promoting new urbanization construction. In this study, cities in the upper reaches of the Yangtze River (URYR) were adopted as the research object, a theoretical analysis framework for the urban land use efficiency (ULUE) and ecological environment quality (EEQ) was established, the ULUE was measured by using the Slacks-Based Measure (SBM) model, the coupling coordination and interactive corresponding response relationship between the ULUE and EEQ were analyzed, and the influencing factors of the coupling coordination between these two systems were explored by using the random forest model.

Effect and mechanism of chlorogenic acid on cognitive dysfunction in mice by lipopolysaccharide-induced neuroinflammation.

Background: Neuroinflammation is an important factor causing numerous neurodegenerative pathologies. Inflammation can lead to abnormal neuronal structure and function and even death, followed by cognitive dysfunction. There is growing evidence that chlorogenic acid has anti-inflammatory effects and immunomodulatory activity.

Chinese version of - A self-report video game for assessing mental health in young children.

Objectives: Assess the validity of the Chinese version of the (DI), a 91-item, video-based diagnostic screening instrument for children that assesses four internalized disorders (phobias, separation anxiety disorder, generalized anxiety disorder, and major depressive disorder) and three externalized disorders (attention-deficit/hyperactivity disorder, conduct disorder, oppositional defiant disorder).

Methods: (1) Compare DI-generated "probable" or "possible" diagnoses to diagnoses based on the Development and Well-Being Assessment (DAWBA) instrument in 113 psychiatric outpatients and 20 community controls. (2) Administer DI to 1,479 children from elementary schools in Tianjin.

Deciphering the pharmacological mechanisms of Fraxini Cortex for ulcerative colitis treatment based on network pharmacology and in vivo studies.

Background: Ulcerative colitis (UC) is a common type of inflammatory bowel disease. Due to the elusive pathogenesis, safe and effective treatment strategies are still lacking. Fraxini Cortex (FC) has been widely used as a medicinal herb to treat some diseases.

Cinnamaldehyde Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating TLR4/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation.

Ulcerative colitis (UC) is a chronic inflammatory gastrointestinal disease mainly associated with immune dysfunction and microbiota disturbance. Cinnamaldehyde (CIN) is an active ingredient of Cinnamomum cassia with immunomodulatory and anti-inflammatory properties. However, the therapeutic effect and detailed mechanism of CIN on UC remains unclear, and warrant further dissection.

Help-Seeking Behaviors and Related Factors in Chinese Patients With Major Depressive Disorder: A Community-Based Cross-Sectional Study.

Background: Although evidence-based and effective treatments are available for people with major depressive disorder (MDD), a substantial number do not seek or receive help. Therefore, this study aimed to (1) investigate the total help-seeking rate and first-time help-seeking choices; (2) explore the perceived helpfulness of 23 potential sources; and (3) evaluate the factors related to help-seeking behaviors among patients with MDD.

Materials And Methods: Data came from the Tianjin Mental Health Survey (TJMHS), which included a representative sample of adult community residents ( = 11,748) in the Chinese municipality of Tianjin.

Spatial Transformation Characteristics and Conflict Measurement of Production-Living-Ecology: Evidence from Urban Agglomeration of China.

The land development by human beings has changed from the initial small-scale and low-level transformation to the comprehensive utilization of large-scale and high-intensity implementations. The contradiction between production-living-ecology space (PLES) has become increasingly prominent while drawing land dividends. As one of the important birthplaces of Chinese civilization and the ecological barrier in the northern region, the rapid urbanization and industrialization of the Yellow River Basin (YRB) make the ecological environment very fragile, and the imbalance of land and space development is extremely serious.

Study on the Spatiotemporal Evolution and Influencing Factors of Urban Resilience in the Yellow River Basin.

The outbreak of COVID-19 has prompted consideration of the importance of urban resilience. Based on a multidimensional perspective, the authors of this paper established a comprehensive evaluation indicator system for evaluating urban resilience in the Yellow River basin (YRB), and various methods such as the entropy value method, Theil index, exploratory spatial data analysis (ESDA) model, and geographical detector model were used to measure the spatiotemporal characteristics and influencing factors of urban resilience in the YRB from 2011 to 2018. The results are as follows.