Publications by authors named "Xuxu Lin"
Skin is the body's largest organ, and the main function of skin is to protect underlying organs from possible external damage. Melanocytes play an important role in skin pigmentation. The Bama pig has a "two-end-black" phenotype with different coat colors across skin regions, e.
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- Tibetan pigs have adapted to high altitudes, but research on their gene expression and DNA methylation changes when acclimating to low altitudes is lacking.
- A comparative analysis of skeletal muscle from high-altitude and low-altitude Tibetan pigs showed significant differential gene expression, particularly for genes related to hypoxia response and energy metabolism, but without major DNA methylation changes.
- Notably, genes like SIN3A exhibited increased expression with hypomethylation, while CACNG6 displayed reduced expression with increased methylation, suggesting that DNA methylation plays a role in gene expression changes during low-altitude acclimation.