Publications by authors named "Xuxu Ding"
Article Synopsis
- Cross-contamination of cell lines is a significant issue in research, but short tandem repeats (STR) analysis has served as a reliable method for authenticating these cell lines for over two decades.
- A new comparison of 21-loci STR methods versus the traditional 9-loci approach shows a dramatic 97.5% reduction in uncertainty for cell line authentication, effectively minimizing false positives.
- The study highlights that using the additional loci not only enhances the specificity of markers but also suggests that updating STR databases with more loci could improve the overall accuracy and efficiency of cell line authentication, thereby reducing experimental costs.
