Dual-signal ratiometric electrochemical aptasensor for Zearalenone detection based on magnetic-assisted enrichment and hybridization chain reaction.

In this work, a dual-signal ratiometric electrochemical aptasensor based on the hybrid chain reaction (HCR) and streptavidin-modified magnetic beads (SA-MBs) was developed to rapidly detect zearalenone (ZEN). The HCR, as a powerful signal amplification technique to imporve the signal of sonser. When the target is present, they specifically bind with ZEN-Apt and release ZEN-cDNA to trigger HCR.

Chemiluminescence detection of kanamycin by DNA aptamer regulating peroxidase-like activity of CoO nanoparticles.

Kanamycin (KAN) is widely used as a growth hormone analog and an antibacterial agent. However, abuse of this substance has resulted in the accumulation of excessive residue levels in foods of animal origin, which presents a significant risk to human health. A chemiluminescent aptasensor was constructed for the rapid quantitative detection of KAN by combining the properties of CoO nanoparticles (CoO NPs) nanozyme activity and DNA aptamer with high specificity.

Intracranial mesenchymal tumor with multiple extracranial metastases: A case report and literature review.

This study presents a rare case of an older woman with an intracranial mesenchymal tumor in the right frontal and parietal lobes. Despite prompt surgical intervention, her condition rapidly deteriorated because of tumor dissemination, leading to her demise. We highlight the tumor's marked invasiveness and heterogeneity, coupled with a propensity for distant systemic metastasis, which negatively impacted the patient's prognosis.

Sound Field Reconstruction Using Prolate Spheroidal Wave Functions and Sparse Regularization.

Near-field acoustic holography (NAH) based on compressing sensing (CS) theory enables accurate reconstruction of sound fields using a limited number of sampling points. However, the successful implementation of this technique depends on two crucial factors: (1) the appropriate selection or construction of the spatial basis and (2) an effective sparse regularization process. To enhance reconstruction performance for elongated sound sources, this paper proposes a novel sound field reconstruction method that combines prolate spheroidal wave functions (PSWFs) with the orthogonal matching pursuit (OMP) algorithm.

Risk Assessment Model System for Aquatic Animal Introduction Based on Analytic Hierarchy Process (AHP).

The spread of invasive species (IS) has the potential to upset ecosystem balances. In extreme cases, this can hinder economical utilization of both aquatic (fisheries) and terrestrial (agricultural) systems. As a result, many countries regard risk assessment of IS as an important process for solving the problem of biological invasion.

DNA metabarcoding uncovers the diet of subterranean rodents in China.

Objective: A type of rodent called a zokor causes great harm to agriculture and forestry production due to its large and sophisticated diet. As this rodent lives subterrane for most of its life, researchers know little about its dietary habits. Further understanding of its diet is important for developing green and sustainable control strategies for the zokor.

The associations between intestinal bacteria of Eospalax cansus and soil bacteria of its habitat.

Background: Intestinal bacteria of mammal can be influenced by many factors, environmental bacteria is an important factor. However, there are few studies on the interactions between environmental bacteria and intestinal bacteria in wild mammals. To explore the associations between the intestinal bacteriome and the related environmental bacteriome, the intestinal bacterial communities of Eospalax cansus at three different sites and the bacterial communities of the surrounding soil (outside and inside the cave) at each site were investigated by 16S rRNA sequencing.

Safety assessment of trucks based on GPS and in-vehicle monitoring data.

Increasingly, drivers are choosing to buy usage-based automobile insurance (UBI). Manage-how-you-drive (MHYD) insurance, a new type of UBI, incorporates active safety management to monitor driver behavior and issue warnings as needed. While researchers have introduced telematics data into automobile insurance pricing, the specific effect of in-vehicle active safety management on driver risk assessment has been neglected, especially for truck drivers, whose crashes have more serious consequences.

Effect of daily car-following behaviors on urban roadway rear-end crashes and near-crashes: A naturalistic driving study.

The rear-end crash is one of the most common types of crashes, and key risk factors have been broadly identified in the car-following behaviors preceding a crash. However, the relationships between rear-end crash risk and daily car-following behaviors, or habits, have not been well examined. This study aims to identify the daily car-following behaviors on urban surface roads and urban expressways that have the most influence on rear-end crashes and near-crashes (CNC).

Functional differentiation related to decomposing complex carbohydrates of intestinal microbes between two wild zokor species based on 16SrRNA sequences.

Background: The intestinal microbes in mammals play a key role in host metabolism and adaptation. As a subterranean rodent, zokor digs tunnels for foraging and mating. These digging activities of zokors increase the energy expenditure relative to their aboveground counterparts.

The influence of cell morphology on microfluidic single cell analysis.

Microfluidics has been widely used in single cell analysis. Current protocols allow either spread or round cells to be analyzed. However, the contribution of cell morphology to single cell analysis has not been noted.

Investigating factors influencing drivers' speed selection behavior under reduced visibility conditions.

Objective: Driving speed is a major concern for driving safety under reduced visibility conditions. Many factors affect speed selection in low visibility, but few studies have been conducted examining drivers' characteristics, particularly in China. The present study aimed to investigate the correlation between drivers' demographic information, driving ability, and speed choice in low-visibility conditions using a sample of Chinese drivers.

Distinguishing Intracerebral Hemorrhage from Acute Cerebral Infarction through Metabolomics.

Background: Acute cerebral infarction (ACI) and intracerebral hemorrhage (ICH) are potentially lethal cerebrovascular diseases that seriously impact public health. ACI and ICH share several common clinical manifestations but have totally divergent therapeutic strategies. A poor diagnosis can affect stroke treatment.

Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs).

Contents: Danshen is a popular herb employed to treat cardiovascular and cerebrovascular diseases worldwide. Danshen-drug interaction has not been well studied.

Objective: The inhibitory effects of four major tanshinones (tanshinone I, tanshinone IIA, cryptotanshinone, and dihydrotanshinone I) on UDP-glucuronosyltransferases (UGTs) isoforms were determined to better understand the mechanism of danshen-prescription drugs interaction.

[Clinical analysis of microsurgical treatment of giant intracranial arteriovenous malformations].

Objective: To explore the clinical features and microsurgical treatment strategies of giant intracranial arteriovenous malformations (AVM).

Methods: A total of 15 cases of giant intracranial AVM treated with microsurgery were analyzed retrospectively. According to the Spetzler-Martin grade, there were 4 cases of grade Ⅳ, 11 cases of grade Ⅴ.

Effects of progesterone on the growth regulation in classical progesterone receptor-negative malignant melanoma cells.

This study investigated the growth-regulating effects of progesterone (Prog) on nPR-negative malignant melanoma cells and the possible mechanisms. A375 and A875 cells were cultured and treated with Prog of different concentrations. For signal transduction pathway studies, the cells were pretreated with Prog receptor antagonist (RU486, 1 x 10(-7) mol/L) or MAPK inhibitor (U0126, 5 x 10(-6) mol/L) for 1 h and then co-incubated with prog (10(-9) mol/L) for another 24 h.

Up-regulation of human leukocyte antigen G expression in primary cutaneous malignant melanoma associated with host-vs-tumor immune response.

Human leukocyte antigen G (HLA-G) is one of the molecules implicated in immunotolerance. To investigate the role of HLA-G in primary cutaneous malignant melanoma (CMM), a series of 47 skin melanocytic lesions were immunohistochemically evaluated. The correlation between HLA-G expression and CMM clinicohistopathological data and Bcl-2 expression was also analyzed.

[Application of near infrared sensor to the radio control count system].

Using reflective near infrared sensor, radio receiving/transmitting module and four-in-one function mix count integrated circuits, the radio control infrared counter was studied when a product enters the infrared surveillance area, part of the infrared signal will be reflected by the product, received by the photosensitive tube installed parallel with the transmitting tube, and transformed to a similar frequency electric signal, which is amplified by the internal circuits of infrared sensor module. After comparing and processing, a high level signal will be output to start transmitting module. When the receiving device receives the radio control encoded signal, it will demodulate and decode the signal, and send out an encoded pulse.

[Application of pyroelectric infrared sensor to radio control alarm system].

A radio control alarm system was developed, which is composed of a pyroelectric infrared detecting module, a radio receiving/transmitting module, a digital encoding/decoding IC, and a voice recoding/playing module. When somebody enters the surveillance area, the infrared sensor will receive and transform the radiant energy into electric signal, which is amplified by internal circuits, and then generates a control signal to start transmitting system. As the encoded pulse is modulated by the transmitting module, a radio control signal will be spread to space; When received, the signal will be demodulated, amplified, shaped and decoded to trigger the recoding/playing circuits, which play the recoded voice to awake watch people.