Publications by authors named "Xutu Zhao"
Article Synopsis
- The study aimed to assess different surgical reconstruction methods to enhance urinary continence after robot-assisted radical prostatectomy (RARP), a common concern for prostate cancer patients.
- It included patients who underwent various reconstruction approaches and tracked their recovery in terms of continence, sexual function, and quality of life over a few years.
- Results showed that patients who received either single or combined reconstruction techniques had better urinary continence outcomes compared to those who had no reconstruction, with the combined method being the most effective.
Article Synopsis
- Chronic inflammation is a significant factor in the development of cancer, with interleukin 33 (IL-33) being a key player in this process, though its environmental triggers remain unclear.
- A study reveals that the TLR3/4-TBK1-IRF3 signaling pathway links environmental stressors to the induction of IL-33 in skin and pancreatic inflammation.
- Pitavastatin, an FDA-approved drug, effectively reduces IL-33 levels and demonstrates the potential to prevent chronic pancreatitis and its associated cancer through inhibiting the TBK1 pathway, suggesting statins may be a promising approach to combat chronic inflammation-related cancers.
Background: Myopia is a complex disease caused by a combination of multiple pathogenic factors. Prevalence trends and developmental patterns of myopia exhibit substantial variability that cannot be clearly assessed using limited sample sizes. This study aims to determine the myopia prevalence over the past 60 years and trace the myopia development in a school-aged population using medical big data.
View Article and Find Full Text PDFAim: To study the change in ocular refraction in patients with pediatric cataracts (PCs) after lens extraction.
Methods: A total of 1258 patients who were undergoing cataract extraction with/without intraocular lens (IOL) implantation were recruited during preoperative examinations between Jan 2010 and Oct 2013. Patient ages ranged from 1.
Background: Electronic medical records provide large-scale real-world clinical data for use in developing clinical decision systems. However, sophisticated methodology and analytical skills are required to handle the large-scale datasets necessary for the optimisation of prediction accuracy. Myopia is a common cause of vision loss.
View Article and Find Full Text PDFAim: To investigate the characteristics of young adult cataract (YAC) patients over a 10-year period.
Methods: This observational study included YAC patients aged 18-49 years who were treated surgically for the first time at the Zhongshan Ophthalmic Center in China. YAC patients were analysed and compared with patients with childhood cataract (CC) in January 2005 to December 2014.
Background: The majority of rare diseases are complex diseases caused by a combination of multiple morbigenous factors. However, uncovering the complex etiology and pathogenesis of rare diseases is difficult due to limited clinical resources and conventional statistical methods. This study aims to investigate the interrelationship and the effectiveness of potential factors of pediatric cataract, for the exploration of data mining strategy in the scenarios of rare diseases.
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