Publications by authors named "Xusen Yang"
Childs Nerv Syst
July 2023
Article Synopsis
- The study examines the link between folate metabolism gene polymorphisms and neural tube defects (NTDs) in a Chinese population, comparing 495 affected children with 255 healthy controls.
- Results showed that children with NTDs had lower levels of folic acid, SAM, and a decreased SAM/SAH ratio, while certain environmental factors and the MTHFR 677C > T gene increased NTD risk, whereas the MTHFR 1298A > C gene offered protection.
- Overall, the research highlights the importance of metabolic markers and genetic factors in the incidence of NTDs, suggesting that both genetic predispositions and environmental influences contribute to the condition.
