Ribonucleotide reductase subunit M2 promotes proliferation and epithelial-mesenchymal transition via the JAK2/STAT3 signaling pathway in retinoblastoma.

Retinoblastoma (RB) is an intraocular malignant tumor that often occurs in children. Along with the improvement of treatment strategies, the cure rate of RB has increased significantly. However, the treatment of advanced and recurrent RB remains as a critical challenge.

WITHDRAWN: Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury and .

This paper was originally published in Aging Advance Online Publications on November 29, 2020. In compliance with Aging's withdrawal policy, the paper was withdrawn in its entirety. It will not appear in Aging internal or any external indexes or archives.

Performance evaluation of two fundus oculi angiographic imaging system: Optos 200Tx and Heidelberg Spectralis.

The present study aimed to compare the imaging performance of two ultra-wide-field fluorescein angiography imaging systems, namely the OptosOptomap 200Tx (Optos 200Tx) and the Heidelberg Spectralis (Spectralis). A total of 18 patients (36 eyes) underwent angiography using the two systems at the Department of Ophthalmology, Beijing Friendship Hospital (Beijing, China) between January and June 2017. The images were obtained as a single shot centered on the macula.

Choroidal vascular changes in internal carotid artery stenosis: a retrospective cohort study in Chinese population.

Background: To evaluate choroidal vascularity index (CVI) in eyes with internal carotid artery (ICA) stenosis using binarization tool in enhanced depth images scanned by spectral domain optical coherence tomography.

Methods: A retrospective cohort study was conducted in 142 patients with ICA stenosis, and 20 normal control subjects matched with the age, sex, etc. According to the diagnostic criteria, the participants are divided into a normal control group (20 cases), a mild stenosis group (64 cases), a moderate stenosis group (61 cases), and a severe stenosis group (17 cases).

The mechanism of controllable dehydrogenation: CPMD study of M(BH4)x(NH3)y (M = Li, Mg) decomposition.

Amine metallic borohydrides were synthesized as a new series of hydrogen-storage materials. Their dehydrogenation can be controlled if appropriate metal centres are chosen. A typical example is LiBH4NH3 (ALB) and Mg(BH4)2(NH3)2 (AMgB) adopt the same symmetries but show totally different appearances when decomposed.