Publications by authors named "Xunping Wu"
Cell Signal
December 2024
Article Synopsis
- Skin cutaneous melanoma (SKCM) is an aggressive cancer arising from melanocytes, and there is an urgent need for new drug targets since current treatments have limitations.
- The study investigated ARNTL (Bmal1), finding reduced expression in SKCM tissues, which correlates with poor prognosis and immune infiltration, suggesting its role in the tumor microenvironment.
- Bmal1 overexpression was shown to inhibit melanoma cell growth and invasion, positioning it as a potential biomarker for diagnosing and predicting the progression of SKCM.
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