High serum EDA concentration is associated with metabolic syndrome and its determinants.

Background: Ectodysplasin A (EDA) is a novel hepatokine that plays a role in multiple metabolic-related diseases. The aim of this study was to investigate the association between serum EDA levels and metabolic syndrome (MetS).

Methods: A total of 348 subjects, 258 patients with MetS and 90 healthy controls were enrolled.

Association of Serum Tsukushi Levels with Urinary Albumin-Creatinine Ratio in Type 2 Diabetes Patients.

Objective: Tsukushi is a newly identified hepatokine. Recent studies have shown that it relates to diabetes, lipid metabolism and fibrosis, but there is currently no investigation about whether Tsukushi is associated with diabetic kidney disease. Therefore, this study aimed to investigate the relationship between Tsukushi and diabetic kidney disease by characterizing Tsukushi levels in healthy subjects and type 2 diabetes with urinary albumin-creatinine ratio.

Sex differences in association of healthy eating pattern with all-cause mortality and cardiovascular mortality.

Background: Although the Healthy Eating Index (HEI) is widely recommended to reduce the risk of cardiovascular disease and all-cause death, there are significant differences in physiological and nutritional factors between the sexes. The potential impact of sex on adult dietary health is still poorly understood. The study was designed to assess whether the health benefits of diet differed by sex.

Associations between new obesity indices and abnormal bone density in type 2 diabetes mellitus patients.

Unlabelled: The clinical data analysis found that, compared with the traditional obesity index, the waist-weight ratio (WWR) has more advantages in predicting abnormal bone mineral density in subjects with type 2 diabetes. WWR may serve as a new predictive indicator for osteoporosis in T2DM patients.

Purpose: This study was designed to explore the correlation between obesity-related indices and bone mineral density (BMD) and its influencing factors in type 2 diabetes mellitus (T2DM) patients.

Simulation of the activation of mining faults and grouting reinforcement under thick loose layer and thin bedrock.

We have investigated the activation characteristics of mining faults and the effect of grouting reinforcement under thick loose layer and thin bedrock of the working face and evaluate their impact on the safety of mining at similar working faces. Implementing the geological conditions of the 331 working face of the Yangcun Coal Mine (China) of the Yankuang Energy Group Corporation, we have analyzed mechanically the process of fault activation at first. Subsequently, we have obtained the mechanical criterion of fault slip and the expression of relative strength of the nearby rock mass.

Rock Damage Model Coupled Stress-Seepage and Its Application in Water Inrush from Faults in Coal Mines.

Mining-induced fractures often constitute water inrush channels, which lead to mine water inrush accidents. In this paper, a coupled model of stress-seepage-damage based on micromechanics is established, which simulates the initiation and propagation of cracks in rock materials and their interaction with fluid flow. The method combines the continuous damage model with the effective stress principle, in which the elastic modulus and permeability are related to the damage variables.

Mathematical Evaluation on the Control of Mining-Induced Ground Subsidence in Thick Loose Strata.

Coal mining under thick loose strata in North China leads to ground subsidence, which is a natural result of hydromechanical coupling (fluid flow coupled with solid deformation). Therefore, the land surrounding the mining areas is greatly damaged. In this study, the combined weight (CW) method and the fuzzy matter-element analysis (FMEA) method were used to analyze and evaluate the control effect of subsiding land.

Serum Tsukushi levels are elevated in newly diagnosed type 2 diabetic patients.

Aims: Tsukushi, a newly identified hepatokine, has been recently characterized as a potent modifier in lipid metabolism and energy homeostasis, but the role of Tsukushi in diabetes remains almost unknown. We detected for the first time the serum Tsukushi levels in newly diagnosed type 2 diabetes, exploring the relationship between Tsukushi and various metabolic parameters.

Methods: A total of 172 participants were recruited, including 86 patients with newly diagnosed type 2 diabetes and 86 subjects with normal glucose tolerance according to oral glucose tolerance test.

Visceral Fat Area, Not Subcutaneous Fat Area, is Associated with Cardiac Hemodynamics in Type 2 Diabetes.

Background: This study was conducted in patients with type 2 diabetes mellitus (T2DM) to assess the association between visceral fat area (VFA) and cardiac hemodynamics.

Methods: A total of 568 patients with type 2 diabetes (mean age 54±12 years; 40.8% of women) were enrolled.