From pill to pain: Alendronate-induced esophageal injury-A case report and review.

Background: Alendronate is used to treat Paget's bone disease, glucocorticoid-induced osteoporosis, and postmenopausal osteoporosis because it suppresses osteoclast activity to stop bone resorption.

Case Report: We present an exceptional case of esophagitis caused by alendronate. Blood tests and other data were normal when the patient was taken to the hospital, but an endoscopic examination revealed significant esophageal redness, erosion, and ulceration, along with pseudomembrane.

An experimental study on stress-shielding effects of locked compression plates in fixing intact dog femur.

Background: In orthopedic application, stress-shielding effects of implant materials cause bone loss, which often induces porosis, delayed bone healing, and other complications. We aimed to compare the stress-shielding effects of locked compression plate (LCP) and limited-contact dynamic compression plate (LC-DCP) in dogs with plate-fixed femurs.

Methods: Bilateral intact femurs of 24 adult dogs were fixed by adult forearm 9-hole titanium plates using minimally invasive plate osteosynthesis (MIPPO) technology, with LCP on the left and LC-DCP on the right femurs.

Intrinsically Visible Light-Responsive Liquid Crystalline Physical Gels Driven by a Halogen Bond.

Photoresponsive physical gels using liquid crystals (LCs) as solvents have attracted great interest owing to their potential applications. But, current investigations mainly focus on UV light, which is not environment-friendly enough. On the other hand, the halogen bond is a novel tool for constructing supramolecular gels because of good hydrophobicity, high directionality, tunable strength, and large size of halogen atoms.

Visible light-triggered gel-to-sol transition in halogen-bond-based supramolecules.

Photoresponsive supramolecular gels have aroused continuous attention because of their extensive applications; however, most studies utilize UV light, which inevitably brings about some health and environmental issues. The halogen bond is an important driving force for constructing supramolecules due to its high directionality, tunable strength, good hydrophobicity, and large size of the halogen atoms. Yet, it still remains a formidable challenge to utilize halogen bonds as a driving force to fabricate a visible light responsive gel.

Prevalence and Antimicrobial Susceptibility of Mycobacterium abscessus in a General Hospital, China.

Objective: To gain greater insight into the prevalence drug resistant profiles of M. abscessus from a general hospital in Beijing, China.

Methods: Partial gene sequencing of 16S, hsp65, and rpoB were used to distinguish the species of NTM isolates.

[Comparison of casting precision of two kinds of commercially available gypsum-bonded investment with different setting and thermal expansion characteristics].

Objective: To investigate expansion characteristics of two kinds of commercial investment (Cristo balite Micro II and Cristo Quick), and their effects on cast accuracy of a dental Ag-Pd casting alloy.

Methods: Two kinds of investment were mixed at the ratio of 1:3. The setting and thermal expansion curves of the investment were recorded according to the requirements of ISO7490 and expansion rate calculated, respectively.