Synopsis of recent research by authors named "Xulin Pan"
- Xulin Pan's research primarily focuses on the design and analysis of bioactive compounds, particularly those with potential therapeutic applications, using computational techniques such as density functional theory (DFT) and 3D quantitative structure-activity relationship (QSAR) studies.
- Findings include the discovery of multiple hydrogen-bonding interactions in macrocyclic compounds for anion binding, the isolation of cytotoxic cyclotides from plants, and the development of predictive models for inhibitors of human cathepsin K and carbonic anhydrase II.
- The research emphasizes the importance of molecular modeling and structural analysis in drug design, showcasing significant advancements in understanding the inhibitory activities of various bioactive molecules against relevant enzyme targets in disease pathology.
