Publications by authors named "Xulang Xiao"
The oligosaccharide Hep-2 from cultured mycelium of Hericium erinaceus was obtained with a hollow-fiber ultrafiltration cartridge and purified with a DEAE Sephadex A-50 column followed by a Bio-Gel P-30 column. The properties, structure, and antioxidant activities of Hep-2 were studied. Hep-2 had the molecular weight of 1,080 Da and consists of Glc and Gal in a molar ratio of 1.
View Article and Find Full Text PDFHericium erinaceus is typically used in traditional Chinese medicine for mucosal protection, healing of gastric ulcers, and treatment of gastritis. We purified from the cultured mycelia of H. erinaceus a polysaccharide with anti-gastric ulcer and antigastritis activity, but its effects on gastric malignancy have not been elucidated.
View Article and Find Full Text PDFArticle Synopsis
- Hericium erinaceus (HE) is a traditional remedy used for treating gastric issues, and EP-1, a polysaccharide from HE mycelium, is identified as its key active ingredient against gastritis.
- EP-1 exhibits significant antioxidant properties, showing a higher capacity to neutralize harmful radicals compared to a hot water extract of HE.
- In experiments with gastric cells, EP-1 protected against oxidative stress and apoptosis caused by hydrogen peroxide, proving to be more effective than the crude mycelial polysaccharide extract (CMPS) of HE.