High-dimensional spin-orbital single-photon sources.

Hybrid integration of solid-state quantum emitters (QEs) into nanophotonic structures opens enticing perspectives for exploiting multiple degrees of freedom of single-photon sources for on-chip quantum photonic applications. However, the state-of-the-art single-photon sources are mostly limited to two-level states or scalar vortex beams. Direct generation of high-dimensional structured single photons remains challenging, being still in its infancy.

Off-Normal Polarized Single-Photon Emission with Anisotropic Holography Metasurfaces.

Solid-state quantum emitters (QEs) with arbitrary direction emission and well-defined polarization are critical for scalable single-photon sources and quantum information processing. However, the design strategy for on-chip generation of off-normal photon emission with high-purity polarization characteristics has so far remained elusive. Here, we introduce the anisotropic holography metasurfaces for efficiently manipulating the emission direction and polarization of QE.

Tempering Multichannel Photon Emission from Emitter-Coupled Holographic Metasurfaces.

On-chip manipulation of photon emission from quantum emitters (QEs) is crucial for quantum nanophotonics and advanced optical applications. At the same time, the general design strategy is still elusive, especially for fully exploring the degrees of freedom of multiple channels. Here, the vectorial scattering holography (VSH) approach developed recently for flexibly designing QE-coupled metasurfaces is extended to tempering the strength of QE emission into a particular channel.

Expression of apelin‑13 and its negative correlation with TGF‑β1 in patients with diabetic kidney disease.

Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes, one key feature of which includes renal fibrosis. As apelin is an adipokine closely related to diabetes, the present study aimed to evaluate apelin-13 expression levels and the relationship between apelin-13 and disease indicators in patients with diabetic kidney disease (DKD). The present case-control study enrolled 70 patients with diabetes, including 31 with diabetic kidney disease (DKD group), 39 without DKD (non-DKD group) and 30 healthy controls.

Multichannel Quantum Emission with On-Chip Emitter-Coupled Holographic Metasurfaces.

Multichannel quantum emission is in high demand for advanced quantum photonic applications such as quantum communications, quantum computing, and quantum cryptography. However, to date, the most common way for shaping photon emission from quantum emitters (QEs) is to utilize free-standing (external) bulky optical components. Here, we develop the multichannel holography approach for flexibly designing on-chip QE-coupled metasurfaces that make use of nonradiatively QE-excited surface plasmon polaritons for generating far-field quantum emission, which propagates in designed directions carrying specific spin and orbital angular momenta (SAM and OAM, respectively).

On-chip generation of single-photon circularly polarized single-mode vortex beams.

Generation of single photons carrying spin and orbital angular momenta (SAM and OAM) opens enticing perspectives for exploiting multiple degrees of freedom for high-dimensional quantum systems. However, on-chip generation of single photons encoded with single-mode SAM-OAM states has been a major challenge. Here, by using carefully designed anisotropic nanodimers fabricated atop a substrate, supporting surface plasmon polariton (SPP) propagation, and accurately positioned around a quantum emitter (QE), we enable nonradiative QE-SPP coupling and the SPP outcoupling into free-space propagating radiation featuring the designed SAM and OAM.

Ultracompact Single-Photon Sources of Linearly Polarized Vortex Beams.

Ultracompact chip-integrated single-photon sources of collimated beams with polarization-encoded states are crucial for integrated quantum technologies. However, most of currently available single-photon sources rely on external bulky optical components to shape the polarization and phase front of emitted photon beams. Efficient integration of quantum emitters with beam shaping and polarization encoding functionalities remains so far elusive.

Rate-Dependent Pattern Evolution in Peeling Adhesive Tape Driven by Cohesive Failure.

In the case of low-rate peeling, an adhesive can undergo a large tensile deformation through the viscous flow and form the fingering pattern at the peeling interface, resulting in homogeneous stripes on the peeled surface. In the case of high-rate peeling, no larger viscous deformation occurs, and no surface patterns will be generated. However, it is still unclear how the surface pattern evolves when an adhesive is peeled from a relatively low rate to a high rate.

A case report of severe adverse reaction of exenatide: Anaphylactic shock.

Background: Anaphylactic shock is the severe state of the allergic reaction, which is rapid in onset and fatal. This is the first study that discusses the anaphylactic shock of exenatide reexposure in the patient who has interrupted exenatide treatment.

Patient Concerns: A 47-year-old man was treated with exenatide owing to high blood glucose and obesity.

PK/PD integration of florfenicol alone and in combination with doxycycline against .

(RA) is an important pathogen found in poultry. RA infection can kill ducks and lead to significant economic losses. Seven RA strains with different susceptibility phenotypes were chosen to study the pharmacokinetic/pharmacodynamic (PK/PD) integration of florfenicol (FF) alone and in combination with doxycycline (DOX).

[Preparative isolation and purification of scopoletin from Lycium barbarum L. by high-speed countercurrent chromatography].

An effective and rapid method for the separation of scopoletin from Lycium barbarum L. by high-speed counter-current chromatography (HSCCC) was established. The ethyl alcohol extract of the Lycium barbarum L.

Safety evaluation of main alkaloids from Rhizoma Coptidis.

Ethnopharmacological Relevance: Rhizoma Coptidis (RC), a widely used traditional Chinese medicine, has been used for the treatment of heat-clearing and detoxifying, but there is very little information on its safety.

Aim Of The Study: To provide information on the safety of RC, we evaluated the toxicity of the crude RC and RC alkaloids (berberine, coptisine, palmatine and epiberberine) including cytotoxicity, acute toxicity in mice and sub-chronic toxicity in rats.

Materials And Methods: The cytotoxicity of RC alkaloids was tested in HepG2 and 3T3-L1 cells by the MTT assay.

Insulin-like growth factor II and binding proteins 1 and 3 from second trimester human amniotic fluid are associated with infant birth weight.

The developing fetus begins to swallow amniotic fluid (AF) early in gestation, a process that results in ingestion of numerous growth factors. Our objectives were 2-fold: 1) to assess the concentration and distribution of insulin-like growth factor II (IGF II) and its binding proteins (BP) 1 and 3 in 2nd trimester amniotic fluid using ELISA, and 2) to establish whether concentrations of AF IGF II and its binding proteins IGF BP1 and 3, measured early in pregnancy, were associated with and predictive of infant birth weight. Birth weights were categorized using recently developed birth-weight-for-gestational-age percentiles for fetal growth in which infants < 10% were classified as SGA (small-for-gestational-age) and those > 90% as LGA (large-for-gestational-age).