ALGD-ORB: An improved image feature extraction algorithm with adaptive threshold and local gray difference.

Simultaneous Localization and Mapping (SLAM) technology is crucial for achieving spatial localization and autonomous navigation. Finding image features that are representative presents a key challenge in visual SLAM systems. The widely used ORB (Oriented FAST and Rotating BRIEF) algorithm achieves rapid image feature extraction.

Prospects and hot spots for mammalian target of rapamycin in the field of neuroscience from 2002 to 2021.

Mammalian target of rapamycin (mTOR) is an important molecule that regulates cell metabolism, growth, and proliferation in the nervous system. This study aimed to present the current study hot spots and predict the future development trend of the mTOR pathway in neurologic diseases using bibliometrics. We referred to the publications in the Web of Science Core Collection database.

[Advances on gene-based association analysis].

Genome-wide association studies (GWAS) have been widely used for hunting the susceptibility genes for common diseases in the past years; however, the abundant information for the disease mechanism based on the GWAS data has not been fully mined. Recently, some researchers focused on the biological network and pathway analysis for the GWAS data to explore the potential disease mechanism. Since genes are the basic units for the biological network and pathway, the genetic effects from all or part of single nucleotide polymorphisms (SNPs) in the genes should be integrated into genetic scores, which are so-called "gene-based association analysis".

Identification of susceptibility modules for coronary artery disease using a genome wide integrated network analysis.

Although recent genome-wide association studies (GWAS) have identified a handful of variants with best significance for coronary artery disease (CAD), it remains a challenge to summarize the underlying biological information from the abundant genotyping data. Here, we propose an integrated network analysis that effectively combines GWAS genotyping dataset, protein-protein interaction (PPI) database, literature and pathway annotation information. This three-step approach was illustrated for a comprehensive network analysis of CAD as the following.