Publications by authors named "Xufei Duan"

Background And Aim: Chronic pancreatitis (CP) in children has exhibited an annual increase in incidence in recent years. Pediatric CP presents unique clinical features compared to adult cases. Endoscopic retrograde pancreatography (ERP) serves as a valuable and safe tool for diagnosing and treating CP in adults.

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  • * A total of 35 carbamate derivatives were synthesized using a green oxidation method and evaluated for their antifungal activity against seven plant pathogens, showing promising results.
  • * Two specific compounds demonstrated exceptional antifungal performance, suggesting their potential as lead candidates for future antifungal drug development.
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This paper reports the diagnosis and treatment process of a case of fetal mesenchymal hamartoma of the liver (MHL), and reviews the previous literature reports. At 38 weeks of gestation, prenatal ultrasound found a well bound mixed solid and cystic mass, which was located at the lower edge of the right lobe of the liver and in front of the right kidney of the fetus, but the source and nature of the mass were not clear by ultrasound. Due to the approaching due date, the fetus showed no other abnormal symptoms, and no special treatment was given with the consent of the family members.

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Purpose: Establish and validate a nomogram to help predict the preoperative risk of a pathological intussusception.

Methods: A primary cohort of patients who underwent surgery for an intussusception were enrolled from one center, while a validation cohort consisted of patients from another center. Multivariate logistic regression analysis was used to identify the variables to build the nomogram.

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Objective: This study aimed to explore the etiology, clinical features, diagnosis, and treatment of spontaneous bile duct perforation (SBDP) in children.

Methods: The clinical data of children with SBDP who were admitted to Wuhan Children's Hospital between January 2014 and January 2020 were retrospectively analyzed.

Results: In all, 28 cases of children with SBDP (male, 28.

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Background: Lipoma is a common benign tumor derived from adipose tissue, with an incidence of nearly 10%. It is the most common mesenchymal tumor throughout the body. However, the pathogenesis of lipoma is not clear yet, and the increased incidence is attributable to obesity, elevated serum cholesterol, diabetes, trauma, radiation, familial predisposition, and chromosome.

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  • Maternal butyrate supplementation in pregnant mice creates a microbiome in newborns that may protect them from biliary atresia, a severe liver condition.
  • This beneficial effect is linked to specific bacterial populations in their feces and changes in stool metabolites, enhancing the pups' resistance to inflammation and injury.
  • In contrast, human neonates with biliary atresia show reduced levels of these protective bacteria and metabolites, suggesting a potential connection between maternal diet, microbiome development, and disease susceptibility in babies.
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Introduction:  Vascular endothelial growth factor (VEGF) and its receptor act as a major contributor to lymphangioma, but their role on nonrecurrent and recurrent lymphangiomas remain unclear. We aim to investigate those factors in the generation of recurrent lymphangioma.

Materials And Methods:  Patients diagnosed with lymphangioma from January 2005 to December 2012 in our hospital were collected and divided into nonrecurrent and recurrent lymphangiomas.

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Objective: We aimed to investigate the role of the intestinal neurotransmitters vasoactive intestinal peptide (VIP) and substance P (SP) at different time points in infants with acute intussusception.

Methods: Thirty patients who were diagnosed with acute intussusception were enrolled in the study and classified as the experimental group. Another 30 patients with an indirect inguinal hernia who had no intestinal injury were included as the control group.

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Objective: The aim of this study was to investigate the pathogenesis, symptoms and individualized surgical management in pediatrics with gastroduodenal perforation (GDP).

Methods: Patients diagnosed with GDP from January 2013 to December 2016 in our hospital were collected and divided into gastric perforation (GP) group and duodenal perforation (DP) group. Demographics, clinical events, etiological factors, symptoms, the time from symptom onset to operation, intraoperative findings and surgical procedures were analyzed.

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  • Biliary atresia (BA) is difficult to diagnose in infants because its symptoms can mimic other causes of neonatal cholestasis, making early diagnosis and treatment crucial for better health outcomes.
  • Recent research suggests that higher levels of serum matrix metalloproteinase-7 (MMP-7) can help distinguish BA from non-BA conditions.
  • In a study of 135 infants, MMP-7 levels were significantly elevated in those with BA, showing high sensitivity (98.67%) and specificity (95.00%) for diagnosing this condition, making it a potential reliable biomarker.
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Background: This study aims to evaluate the utility of the "Cross-Internal Ring" inguinal oblique incision for the surgical treatment of incarcerated indirect hernia (IIH) complicated with severe abdominal distension.

Materials And Methods: Patients of IIH complicated with severe abdominal distension were reviewed retrospectively. All patients received operation through the "Cross-Internal Ring" inguinal oblique incision.

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Background: To discuss the experience of diagnosis and treatment of ovarian cyst in infants.

Materials And Methods: A retrospective review was conducted on 20 infants who suffered from ovarian cyst.

Results: There were no dysplasia ovarian was found in children which were preoperatively diagnosed simplex cyst.

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To investigate the management of Meckel's diverticulum in children and the feasibility of using laparoscopic and laparoscopically assisted Meckel's diverticulum resection and intestinal anastomosis according to the different subtypes classified laparoscopically. 55 symptomatic Meckel's diverticulum cases were classified into two categories, the simple and the complex types depending on Meckel's diverticulum appearance upon laparoscopic exploration. Forty-one cases of simple Meckel's diverticulum were treated with simple diverticulectomy during laparoscopy, and 14 cases of complicated Meckel's diverticulum were treated with laparoscopically assisted Meckel's diverticulum resection and intestinal anastomosis.

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Objective: To determine the detection rate of Helicobacter pylori (Hp) in children with Meckel's diverticulum (MD) and its clinical significance among children with MD.

Methods: Eighty-one children with MD were divided into two groups according to the presence (n=45) or absence (n=36) of digestive hemorrhage. The detection rates of Hp in MD tissues and stomach tissues were determined by immunohistochemistry.

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