Publications by authors named "Xueyun Li"

Fast scanning speed and low-power consumption are becoming progressively more and more important in realizing high-performance chiplet optical phased arrays (OPAs). Here, we successfully demonstrated integrated OPAs with multiple waveguides channels based on thin-film lithium niobate-on-insulator (LNOI) platform. Specifically, two lithium niobate (LN) OPA chips have been implemented with 32 and 48 channels LN waveguides, respectively, enabled by electro-optic modulations, which showcases the low power consumption (1.

View Article and Find Full Text PDF

Objectives: Long COVID has received much attention as a complex multi-system disease due to its serious impact on quality of life. However, there remains inconsistent results in terms of risk factors, and a prediction model for the accurate prediction of long COVID is still lacking.

Study Design: Cross-sectional study.

View Article and Find Full Text PDF

On-chip metasurface for guided wave radiation works as an upgrade of conventional grating couplers, enriching the interconnection between guided wave and free-space optical field. However, the number of controllable parameters in equivalent Jones matrix of on-chip metasurface is limited that restricts the channels for multiplexing. Here, a supercell design based on detour phase and geometric phase has been proposed to reach full-parametric modulation of Jones matrix.

View Article and Find Full Text PDF

Background: Small amounts of DNA from a perpetrator collected during crime-scene investigations can be masked by large amounts of DNA from the victim. These samples can provide important information for the perpetrator's conviction. Short tandem repeat (STR) detection system is not sensitive enough to detect trace amounts of minor components in unbalanced mixed DNA.

View Article and Find Full Text PDF

Avian influenza viruses (AIVs) are the origin of multiple mammal influenza viruses. The genetic determinants of AIVs adapted to humans have been widely elucidated, however, the molecular mechanism of cross-species transmission and adaptation of AIVs to canines are still poorly understood. In this study, two H3N2 influenza viruses isolated from a live poultry market (A/environment/Guangxi/13431/2018, GX13431) and a swab sample from a canine (A/canine/Guangdong/0601/2019, GD0601) were used to investigate the possible molecular basis that determined H3N2 AIV adapting to canine.

View Article and Find Full Text PDF

Wastewater-based epidemiology (WBE) has emerged as a promising tool for monitoring the spread of COVID-19, as SARS-CoV-2 can be shed in the faeces of infected individuals, even in the absence of symptoms. This study aimed to optimize a prediction model for estimating COVID-19 infection rates based on SARS-CoV-2 RNA concentrations in wastewater, and reveal the infection trends and variant diversification in Shenzhen, China following the lifting of a strict COVID-19 strategy. Faecal samples (n = 4337) from 1204 SARS-CoV-2 infected individuals hospitalized in a designated hospital were analysed to obtain Omicron variant-specific faecal shedding dynamics.

View Article and Find Full Text PDF

China has been continuously improving its monitoring methods and strategies to address key infectious diseases (KIDs). After the severe acute respiratory syndrome epidemic in 2003, China established a comprehensive reporting system for infectious diseases (IDs) and public health emergencies. The relatively lagging warning thresholds, limited warning information, and outdated warning technology are insufficient to meet the needs of comprehensive monitoring for modern KIDs.

View Article and Find Full Text PDF

Addressing marine oil spills and industrial water pollution necessitates the development of eco-efficient oil-absorbing materials. With increasing concern for the environment, there is a consensus to decrease the use of petroleum-based polymers. Herein, lightweight poly(lactic acid) (PLA) blend foams with varying thermoplastic polyurethane (TPU) content were fabricated via a solvent-free, eco-friendly supercritical carbon dioxide (scCO) extrusion foaming technology.

View Article and Find Full Text PDF

Objective To investigate the effect of 3-deazaadenosine (3-DAA), an N-methyladenosine (mA) methylation modification inhibitor, on the replication of the Japanese encephalitis virus (JEV). Methods Neuro2a mouse neuroblastoma cells, N9 mouse microglial cells, and BHK baby hamster kidney cells were exposed to JEV and then treated with 3-DAA. JEV was also injected into the footpad of adult C57BL/6 mice, which were then administered 3-DAA intraperitoneally.

View Article and Find Full Text PDF

N6-methyladenosine (m6A) is present in diverse viral RNA and plays important regulatory roles in virus replication and host antiviral innate immunity. However, the role of m6A in regulating JEV replication has not been investigated. Here, we show that the JEV genome contains m6A modification upon infection of mouse neuroblast cells (neuro2a).

View Article and Find Full Text PDF

Purpose: To investigate the prevalence, characteristics, causes, consequences, and predictors of and responses to disruptive behavior toward nurses in the perioperative arena.

Design: A cross-sectional design using a network questionnaire platform.

Methods: Nurses in the perioperative arena were recruited online in March 2020.

View Article and Find Full Text PDF
Article Synopsis
  • Developing a high-strength, sensitive piezoresistive foam has been a challenge, but researchers created an eco-friendly method to fabricate these foams using a unique structure involving coatings and supercritical CO2 foaming.
  • The new segregated poly(ether block amide) (PEBA)/carbon nanostructure (CNS) composites showed improved foam properties, including better conductivity and sensing capabilities, compared to traditional random structures.
  • The optimized foam exhibited a remarkable combination of high sensitivity, large working range, and strong compression strength, making it suitable for applications in monitoring human motion.
View Article and Find Full Text PDF
Article Synopsis
  • The development of clean oil-adsorption materials is essential to tackle issues related to oil spills and oily wastewater, as traditional options can cause secondary pollution.
  • Researchers created fully biodegradable foams using a combination of poly(butylene succinate) and poly(lactic acid) through an eco-friendly foaming process, resulting in materials with excellent oil-adsorption performance.
  • The new foams demonstrated impressive expansion ratios and recyclability over 20 cycles, offering a sustainable solution for oil-adsorption applications.
View Article and Find Full Text PDF

Background: In recent years, mobile health (mHealth) has gradually developed in China, and intelligent medicine has become an important research topic. However, there are still significant problems in mHealth applications (apps). Although healthcare professionals and patients are the main users, few studies have focused on their perceptions of the quality of mHealth apps.

View Article and Find Full Text PDF

With the maturity of the hospital real-time information management system at this stage, the main nursing informatics of the hospital has also been fully developed. Based on the analysis of the application status of medical information technology and Internet technology, the real-time information management system is applied to mobile medical and its development status. This paper realizes the auxiliary system of real-time information push.

View Article and Find Full Text PDF

An integrated way to generate and manipulate higher-order Poincaré sphere beams (HOPBs) is a sought-after goal in photonic integrated circuits for high-capacity communication systems. Here, we demonstrate a novel method for on-chip generation and manipulation of HOPBs through combining metasurface with optical waveguides on lithium niobate on insulator platform. With phase modulation by a diatomic geometric metasurface, guided waves are extracted into free space with a high signal-to-noise ratio in the form of two orthogonal circularly polarized optical vortices which are linearly superposed into HOPBs.

View Article and Find Full Text PDF

Citrinin, a mycotoxin existing in fruits, has nephrotoxicity, hepatotoxicity and embryotoxicity. The effects of citrinin on Leydig cell development in prepuberty remains unclear. Male Sprague-Dawley rats were gavaged with 0, 1, 2.

View Article and Find Full Text PDF

Optical phased array (OPA), as a promising beam steering technology, however, usually suffers from a narrow field of view (FOV) that limits its performances in applications. A miniaturized compact strategy to enlarge the beam steering angle is quite desirable for the solid-state OPA technique. Here an on-chip metasurface-doublet is proposed to offer angle magnification integrated with a port-selected optical phased array.

View Article and Find Full Text PDF

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes asymptomatic or mild symptoms, even rare hospitalization in children. A major concern is whether the pre-existing antibodies induced by low pathogenic human coronaviruses (LPH-CoVs) in children can cross-react with SARS-CoV-2. To address this unresolved question, we analyzed the pre-existing spike (S)-specific immunoglobin (Ig) G antibodies against LPH-CoVs and the cross-reactive antibodies against SARS-CoV-2 in 658 serum samples collected from children prior to SARS-CoV-2 outbreak.

View Article and Find Full Text PDF

Tetramethyl bisphenol A (TMBPA) is a widely used flame retardant. TMBPA has been a toxic to Leydig cells in puberty, but it remains unclear whether TMBPA has a similar inhibitor effect on fetal Leydig cells (FLCs). This study reported morphological and functional alterations of FLCs in the testes of male offspring at birth after in utero exposure to TMBPA.

View Article and Find Full Text PDF

Fluornen-9-bisphenol (BPFL) is used as one of the alternatives for bisphenol A. However, whether BPFL has deleterious effects to the male reproductive system and the underlying mechanism remain unknown. Here, we report the effects of BPFL on Leydig cell development in male rats in puberty.

View Article and Find Full Text PDF

Objective: Although the serine active site containing 1 (SERAC1) protein is essential for cardiolipin remodeling and cholesterol transfer, its physiological role in whole-body energy metabolism remains unclear. Thus, we investigated the role of SERAC1 in lipid distribution and metabolism in mice.

Methods: CRISPR/Cas9 was used to create homozygous Serac1 knockout mice.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessiond5cvhe4krpo9dt0738u03e0lrg22vsic): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once