Dual stimuli-responsive fungicide carrier based on hollow mesoporous silica/hydroxypropyl cellulose hybrid nanoparticles.

The controlled release of pesticides based on nanoparticle platforms has emerged as a new technology for increasing the efficiency of pesticides and for reducing environmental pollution because of their size-dependent and target-modifying properties. In the present study, pH/cellulase dual stimuli-responsive controlled-release formulations (PYR-HMS-HPC) were designed by grafting hydroxypropyl cellulose onto pyraclostrobin-loaded hollow mesoporous silica nanoparticles via an ester linkage. The PYR-HMS-HPC formulations were characterized by Fourier transform infrared spectroscopy, thermogravimetric analyzer, transmission electron microscope and scanning electron microscope.