Prenatal diagnosis of a silver-russell syndrome caused by 11p15 duplication and pedigree analysis.

Introduction: Silver-Russell syndrome (SRS) is an imprinting disorder characterized by intrauterine and postnatal growth retardation. The pathogenic alterations and phenotypes are heterogeneous.

Methods: Here, we present a rare pedigree of duplications with different methylation patterns in 11p15.

Effects of cervical conisation on pregnancy outcome: a meta-analysis.

To assess the effect of cervical conisation on pregnancy outcome, a literature search strategy was conducted to identify all of the references lists of the relevant studies. The fixed or random effect model was used to calculate pooled RRs on the basis of heterogeneity. Twenty-seven publications with n cases and m controls were included in the meta-analysis.