Publications by authors named "Xueyao Liu"

Metal halide perovskites have unique luminescent properties that make them an attractive alternative for high quality light-emitting devices. However, the poor stability of perovskites with many defects and the long cycle time for the preparation of perovskite nanocomposites have hindered their production and application. Here, we prepared the perovskite mesostructures by embedding MAPbBr nanocrystals in the mesopores on the surface of silica nanospheres and mixing the nanospheres with silver nanowires and poly(methyl methacrylate) (PMMA), and further explored their optical properties.

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The nonlinear optical properties of bismuth selenium telluride (BiSeTe), a few-layer two-dimensional topological insulator material, have been investigated in this work. An erbium-doped fiber laser (EDFL) based on BiSeTe (BST) nanosheets as saturable absorber (SA) was demonstrated. The BST SA with saturation intensity and modulation depth of 4.

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Article Synopsis
  • This study establishes normative values for wideband acoustic immittance (WAI) and evaluates its effectiveness in detecting tympanic effusion compared to traditional methods.
  • Researchers analyzed data from subjects with normal hearing and those with type C tympanograms, using Matlab to process the results and create contour plots of WAI.
  • The findings showed that WAI had better diagnostic performance than 226-Hz tympanometry, with a higher sensitivity and specificity for detecting effusion, suggesting it could be a more reliable tool for guiding treatment decisions.
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Purpose: To develop a predictive model using machine learning for levothyroxine (L-T4) dose selection in patients with differentiated thyroid cancer (DTC) after resection and radioactive iodine (RAI) therapy and to prospectively validate the accuracy of the model in two institutions.

Methods: A total of 266 DTC patients who received RAI therapy after thyroidectomy and achieved target thyroid stimulating hormone (TSH) level were included in this retrospective study. Sixteen clinical and biochemical characteristics that could potentially influence the L-T4 dose were collected; Significant features correlated with L-T4 dose were selected using machine learning random forest method, and a total of eight regression models were established to assess their performance in prediction of L-T4 dose after RAI therapy; The optimal model was validated through a two-center prospective study (n=263).

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Background: Accurate classification techniques are essential for the early diagnosis and treatment of patients with diabetic retinopathy (DR). However, the limited amount of annotated DR data poses a challenge for existing deep-learning models. This article proposes a difficulty-aware and task-augmentation method based on meta-learning (DaTa-ML) model for few-shot DR classification with fundus images.

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Article Synopsis
  • The study focused on synthesizing germanene-nanosheets (NSs) using liquid-phase exfoliation to explore their nonlinear saturable absorption properties and structure.
  • The germanene-NSs showed promising saturation intensity and modulation depth values, making them effective saturable absorbers for a mode-locked erbium-doped fiber laser (EDFL).
  • Optimizing the cavity length led to improved EDFL performance, producing 883 fs pulses with an output power of 19.74 mW, highlighting germanene's potential in ultrafast photonics and nonlinear optics.
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To investigate the impact of otitis media with effusion(OME) on school-age children regarding their intelligence level and academic performance, providing guidance for clinical diagnosis and treatment. A total of 34 school-age children with OME were recruited. Children and their guardians were asked to complete the WISC-R intelligence tests and self-designed questionnaires.

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To investigate the long-term rehabilitation outcomes of children with cochlear implants(CI) and provide constructive guidance for clinical application. Fifteen children with unilateral CI over 5 years(CI group) were recruited. Ten children with normal hearing were recruited as the healthy control group.

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This paper reports the generation of fundamental solitons and third-order solitons in an erbium-doped fiber laser (EDFL) by a -polyvinyl alcohol (CGT-PVA) saturable absorber (SA). Stable fundamental solitons at 1559.09 nm at a repetition frequency of 5.

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Objectives: This study aimed to 1) assess the hearing-related Quality of Life (QoL) of children with cochlear implants (CIs) in China and 2) investigate the impact of CI in children and of the socio-demographic backgrounds of their guardians on the hearing-related QoL of children with CIs in the Chinese mainstream education system.

Methods: This study used the Mandarin Children with Cochlear Implants: Parental Perspectives questionnaire (MPP), which assessed the communication capability, auditory perception, self-independence, level of happiness with family, social interaction, academic performance, outcome assessment for CI, and level of family support in children with CIs. Both univariate and multiple linear regression analyses were performed to identify the relationship of CI in children and the socio-demographic backgrounds of their guardians with hearing-related QoL in children with CI.

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Objective: Gestational diabetes mellitus (GDM) is induced by multiple factors, and the microRNAs (miRNAs) are well-known to be implicated in GDM progression. We aimed to explore the functional mechanisms of miR-222 in the inflammatory response in GDM by mediating C-X-C chemokine receptor type 4 (CXCR4) and NLRP3 inflammasomes.

Methods: GDM models were established by intraperitoneal injection of streptozocin, and the levels of miR-222 and CXCR4 in GDM patients' placenta tissues as well as GDM mice' placenta and pancreatic tissues were determined.

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A superantiwetting surface based on low-aspect-ratio hierarchical cylinder arrays (HCAs) was successfully obtained on a silica substrate by colloidal lithography with photolithography. Colloidal lithography is a technique involving transfer of a pattern to a substrate by etching or exposure to a radiation source through a mask composed of a packed colloidal crystal, while photolithography is utilized by which a pattern is transferred photographically to a photoresist-coated substrate, and the substrate is subsequently etched. The surface provides an alternative approach to apply aligned micro-nano integrated structures with a relatively low aspect ratio in superantiwetting.

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The assembly of metal nanoparticles (NPs) can regulate their plasmon resonance properties to pursue the best properties for applications. However, the controllable assembly of large-scale metal NP cluster arrays remains a significant challenge. This paper presents a novel strategy to prepare large-scale Au NP cluster arrays based on colloidal lithography and template-guided self-assembly technique.

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Chemotherapy-induced cytotoxicity in normal cells and organs triggers undesired lesions. Although targeted delivery is used extensively, more than half of the chemotherapy dose still concentrates in normal tissues, especially in the liver. Enabling normal cells or organs to defend against cytotoxicity represents an alternative method for improving chemotherapy.

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In nature, viruses can realize self-mineralization under metal-ion-abundant conditions. Interestingly, the mineralized state is a transition state of the virus when the host is not available. Mammalian viruses that share the similar chemical properties also stand a chance of transformation into a mineralized state.

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Intracellular insulin may exhibit a long-term effect in regulating protein synthesis, DNA synthesis, and gene transcription. However, the intracellular delivery of insulin is a great challenge. Here, we describe how a simple biomineralization modification of insulin can transport it into intact cells on a large scale, leading to a long-term therapeutic effect on diabetes mellitus.

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Background: The early identification of patients at risk of dying from community-acquired pneumonia (CAP) is critical for their treatment and for defining hospital resource consumption. Mid-regional pro-adrenomedullin (MR-proADM) has been extensively investigated for its prognostic value in CAP. However, the results are conflicting.

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This paper provides a facile and cost-efficient method to prepare single-strand DNA (ssDNA) nanocone arrays and hierarchical DNA patterns that were mediated by poly(2-hydroxyethyl methacrylate) (PHEMA) brush. The PHEMA brush nanocone arrays with different morphology and period were fabricated via colloidal lithography. The hierarchical structure was prepared through the combination of colloidal lithography and traditional photolithography.

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One-pot solution mineralization can encapsulate epirubicin (EPI) and pooled siRNAs (Pgp and Bcl-2 siRNAs) in calcium phosphate (CaP). The resulting EPI-RNA-CaP nanocomplexes can achieve a spatial-temporal synchronous effect to full-scale overcome sophisticated multiple drug resistance (MDR) by simultaneous inhibitions of drug efflux and intracellular anti-apoptotic defense to maximize the therapeutic efficacy.

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This paper presents a facile method to fabricate bioinspired polyethylene terephthalate (PET) nanocone arrays via colloidal lithography. The aspect ratio (AR) of the nanocones can be finely modulated ranging from 1 to 6 by regulating the etching time. The samples with the AR value of 6 can present underwater superoleophobicity with the underwater oil contact angle (OCA) of 171.

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Controllable biomineralization modification of cisplatin can alter the drug biodistribution with extended circulation time in blood. These changes increase passive tumor target and decrease non-specific accumulation significantly, which can improve chemotherapeutic effect with minimum side effects.

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Nano-solidified intermedias (NSI) of cisplatin were prepared via biomineralization and applied to reverse the drug resistance of cancers in vitro and in vivo by an alternative internalization pathway.

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