Publications by authors named "Xuexuan Liu"

Article Synopsis
  • - This phase 3 trial assessed the self-amplifying mRNA COVID-19 vaccine, ARCT-154, against the ChAdOx1-S adenovirus-vector vaccine in Vietnam, involving nearly 2,400 adult participants.
  • - Both vaccines had similar safety profiles, with mainly mild-to-moderate side effects and few serious adverse events reported.
  • - ARCT-154 showed higher neutralizing antibody responses and efficacy against COVID-19 compared to ChAdOx1-S, suggesting potential immunological advantages without compromising safety.
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Background: Elevated serum uric acid is detected in pulmonary arterial hypertension (PAH) and is associated with poor patient outcomes. High serum uric acid is an independent risk factor for cardiovascular disease and renal impairment. We analyzed the effects of endothelin receptor antagonism on serum uric acid in PAH patients participating in the Sitaxentan to Relieve Impaired Exercise (STRIDE)-2/2X trial, and the impact of uric acid on 6-minute walk distance (6MWD), time to clinical worsening (TtCW) and survival.

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Unlabelled: Cigarette smoking is highly destructive to individuals and society, and is moderately heritable. We completed a genomewide linkage scan to map loci increasing risk for cigarette smoking in a set of families originally identified because they segregate panic disorder (PD). One hundred forty two genotyped individuals in a total of 12 families were studied (214 subjects analyzed, including non-genotyped individuals).

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