A single-center retrospective analysis of endorectal advancement flaps used for the treatment of simple rectovaginal fistulas.

Objective: To investigate the effectiveness of endorectal advancement flaps for middle and low rectovaginal fistulas.

Methods: A retrospective cohort of 57 patients who underwent surgery via an endorectal advancement flap in the RVF between July 2007 and March 2022 was generated. The clinical features of the patients were reviewed.

MoO nanodots coated suture for combating surgical site infection via antibacterial and anti-inflammatory properties.

Surgical site infection (SSI) significantly affects patient recovery time, health outcomes and quality of life which is closely associated with the use of implants or mesh. Sutures are the most frequently used implants that play a significant role in the development of SSI. Studies have demonstrated that the administration of effective bactericidal and anti-inflammatory treatments can significantly decrease the incidence of SSI.

Knockdown of TOP2A suppresses IL-17 signaling pathway and alleviates the progression of ulcerative colitis.

Background: Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa, with a gradually increasing incidence. Therefore, it is necessary to actively seek targets for the treatment of UC.

Methods: Common differentially expressed genes (DEGs) were screened from two microarray data sets related to UC.

Impact of corporate social responsibility on employee loyalty: Mediating role of person-organization fit and employee trust.

The study explores the impact of employee perceptions of corporate social responsibility (CSR) in improving employee loyalty by examining the direct and indirect role of person-organization fit and employee trust. A convenient sampling technique was employed to collect the data sample. A total of 338 questionnaires were collected at three different China-Pakistan Economic Corridor (CPEC) projects in Pakistan.

Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models.

Myelodysplastic syndromes (MDS) are characterized by daunting genetic heterogeneity and a high risk of leukemic transformation, which presents great challenges for clinical treatment. To identify new chemicals for MDS, we screened a panel of FDA-approved drugs and verified the neutrophil hyperplasia inhibiting role of 17β-estradiol (E2, a natural estrogen) in several zebrafish MDS models (pu.1, irf8 and c-myb).

[Effects of Microbial Fuel Cell Coupled Constructed Wetland with Different Support Matrix and Cathode Areas on the Degradation of Azo Dye and Electricity Production].

In this study, microbial fuel cell coupled constructed wetland (CW-MFC) was constructed for azo dye reactive brilliant red X-3B degradation and electricity production. The effects of support matrix and cathode areas on the degradation of X-3B and the electricity production of CW-MFC were investigated in this work to improve the performance of CW-MFC. The highest decolorization efficiency was 92.

Electrode and azo dye decolorization performance in microbial-fuel-cell-coupled constructed wetlands with different electrode size during long-term wastewater treatment.

Microbial-fuel-cell-coupled constructed wetlands (CW-MFCs) with various cathode layers were used for long-term azo dye wastewater treatment. Their performance was assessed using cathode diameters ranging from 20 to 27.5cm and the influence of plants at the cathode was also examined.