Allogeneic Hematopoietic Stem Cell Transplantation Can Improve Prognosis of Extramedullary Infiltration Positive t(8;21) Acute Myeloid Leukemia.

BACKGROUND In t(8;21) acute myeloid leukemia (AML), patients with extramedullary infiltration (EMI) tend to have worse survival outcomes than those without EMI. However, it is still unclear whether allogeneic hematopoietic stem cell transplantation (allo-HSCT) benefits EMI-positive t(8;21) AML patients. MATERIAL AND METHODS This study retrospectively enrolled 651 t(8;21) AML patients, and analyzed 51 patients with EMI at diagnosis.

Reasoning and causal inference regarding surgical options for patients with low-grade gliomas using machine learning: A SEER-based study.

Background: Due to the heterogeneity of low-grade gliomas (LGGs), the lack of randomized control trials, and strong clinical evidence, the effect of the extent of resection (EOR) is currently controversial.

Aim: To determine the best choice between subtotal resection (STR) and gross-total resection (GTR) for individual patients and to identify features that are potentially relevant to treatment heterogeneity.

Methods: Patients were enrolled from the SEER database.

Highly Efficient Photocatalytic Degradation of Tetracycline by Modifying UiO-66 via Different Regulation Strategies.

Wastewater containing organic pollutants cause potential harm to the environment and human health. A series of zirconium-organic frameworks (UiO-66) and their composites were synthesized by solvothermal methods, including band gap adjustment, heterojunction construction, and metal ion doping. For the model pollutant tetracycline (TC), all of the prepared catalysts could achieve effective degradation of it.

g-CN-modified Zr-Fc MOFs as a novel photocatalysis-self-Fenton system toward the direct hydroxylation of benzene to phenol.

In order to explore a green, economic, and sustainable phenol production process, a heterojunction semiconductor materials g-CN/Zr-Fc MOF was synthesized an synthesis method. With the synergistic effect of photocatalysis and the Fenton effect, the composite could effectively catalyze the direct hydroxylation of benzene to phenol under visible light irradiation. The yield of phenol and the selectivity were 13.