Challenges and opportunities in human dimensions behind cat-wildlife conflict.

Because global anthropogenic activities cause vast biodiversity loss, human dimensions research is essential to forming management plans applicable to biodiversity conservation outside wilderness areas. Engaging public participation is crucial in this context to achieve social and environmental benefits. However, knowledge gaps remain in understanding how a balance between conservation and public demands can be reached and how complicated sociocultural contexts in the Anthropocene can be incorporated in conservation planning.

A review of fine-grained sketch image retrieval based on deep learning.

Sketch image retrieval is an important branch of the image retrieval field, mainly relying on sketch images as queries for content search. The acquisition process of sketch images is relatively simple and in some scenarios, such as when it is impossible to obtain photos of real objects, it demonstrates its unique practical application value, attracting the attention of many researchers. Furthermore, traditional generalized sketch image retrieval has its limitations when it comes to practical applications; merely retrieving images from the same category may not adequately identify the specific target that the user desires.

Recent advances in metal-organic frameworks: Synthesis, application and toxicity.

Metal-organic frameworks (MOFs) are a new class of crystalline porous hybrid materials with high porosity, large specific surface area and adjustable channel structure and biocompatibility, which are being investigated with increasing interest for energy storage and conversion, gas adsorption/separation, catalysis, sensing and biomedicine. However, the practical applications of MOFs make them release into the environment inevitable, posing a threat to humans and organisms. In this article, we cover advances in the currently available MOFs synthesis methods and the emerging applications of MOFs, especially in the biomedical field (therapeutic agents and bioimaging).

A Versatile Integrated Microfluidic Chip Based on Sonic Toothbrush-Assisted Mixing for Analyses of Diverse Biomolecules.

Usually, different assays and instrumentation are required for different types of targets, e.g., nucleic acids, proteins, small molecules, etc.

Nanoscale Zinc-Based Metal-Organic Frameworks Induce Neurotoxicity by Disturbing the Metabolism of Catecholamine Neurotransmitters.

As a group of new nanomaterials, nanoscale metal-organic frameworks (MOFs) are widely applied in the biomedical field, exerting unknown risks to the human body, especially the central nervous system. Herein, the impacts of MOF-74-Zn nanoparticles on neurological behaviors and neurotransmitter metabolism are explored in both and assays modeled by C57BL/6 mice and PC12 cells, respectively. The mice exhibit increased negative-like behaviors, as demonstrated by the observed decrease in exploring behaviors and increase in despair-like behaviors in the open field test and forced swimming test after exposure to low doses of MOF-74-Zn nanoparticles.

Collective decision-making and spatial patterns in orientation of an endemic ungulate on the Tibetan Plateau.

Group living animals form striking aggregation patterns and display synchronization, polarization, and collective intelligence. Though many collective behavioral studies have been conducted on small animals like insects and fish, research on large animals is still rare due to the limited availability of field collective data. We used drones to record videos and analyzed the decision-making and behavioral spatial patterns in orientation of Kiang (Tibetan wild ass, ).

Observation of current-induced switching in non-collinear antiferromagnetic IrMn by differential voltage measurements.

There is accelerating interest in developing memory devices using antiferromagnetic (AFM) materials, motivated by the possibility for electrically controlling AFM order via spin-orbit torques, and its read-out via magnetoresistive effects. Recent studies have shown, however, that high current densities create non-magnetic contributions to resistive switching signals in AFM/heavy metal (AFM/HM) bilayers, complicating their interpretation. Here we introduce an experimental protocol to unambiguously distinguish current-induced magnetic and nonmagnetic switching signals in AFM/HM structures, and demonstrate it in IrMn/Pt devices.

Nanoscale cobalt-based metal-organic framework impairs learning and memory ability without noticeable general toxicity: First in vivo evidence.

Metal-organic frameworks (MOFs) exhibit broad potential applications in the environmental, biomedical, catalyst, and energy fields. However, the currently existing data hardly shed light on their health risks before the MOFs' large-scale usage. In this context, we exploratively investigated the in vivo fate and effect of one representative cobalt-based zeolitic imidazolate framework (ZIF-67) at the nano- (60 nm) and submicron- (890 nm) scales.

A review of organophosphate flame retardants and plasticizers in the environment: Analysis, occurrence and risk assessment.

Organophosphate esters (OPEs) are used as additives in flame retardants and plasticizers. Due to phase out of several congeners of polybrominated diphenyl ethers (PBDEs), the application of organophosphorus flame retardants (OPFRs) is continuously increasing over the years. As a consequence, large amounts of OPEs enter the environment.

A Review of Environmental Occurrence, Fate, and Toxicity of Novel Brominated Flame Retardants.

Use of legacy brominated flame retardants (BFRs), including polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD), has been reduced due to adverse effects of these chemicals. Several novel brominated flame retardants (NBFRs), such decabromodiphenyl ethane (DBDPE) and bis(2,4,6-tribromophenoxy) ethane (BTBPE), have been developed as replacements for PBDEs. NBFRs are used in various industrial and consumer products, which leads to their ubiquitous occurrence in the environment.

Occurrence, fate and risk assessment of BPA and its substituents in wastewater treatment plant: A review.

Several bisphenol analogues (BPs) are gradually replacing bisphenol A (BPA) in many fields, following strict restrictions on the production and use of BPA. The presence of micropollutants in wastewater treatment plants (WWTPs) may pose risks to the aquatic ecosystem and human health. In this review, we outlined the occurrence and fate of BPs in WWTPs, and estimated their potential risks to the aquatic ecosystem.

The utilization of reclaimed water: Possible risks arising from waterborne contaminants.

Increasing interest of seeking substitutable water resources accrues from shortage of freshwater. One of the options considered is reclaimed water (also designated as recycled water) that has been widely used in daily life. Although reclaimed water can serve as a feasible reliever of water pressure, attention about its technologies and potential risks is growing in the meantime.

3D printed gel electrophoresis device coupling with ICP-MS for online separation and detection of metalloproteins.

We successfully developed a strategy to combine a customized gel electrophoresis device with ICP-MS for online separation and detection of metalloproteins. The self-designed horizontal column gel electrophoresis device was rapidly and easily fabricated in the laboratory via 3D printing with a low cost. The feasibility of 3D printing to fabricate this device was investigated by offline separation of commercial protein standards.

A unique Pb-binding flagellin as an effective remediation tool for Pb contamination in aquatic environment.

Metal contaminants present persistent and deleterious threats to environmental ecosystems and human health. Microorganisms can rapidly develop protective mechanisms against metal toxicity, such as metallothionein production. The identification of biological factors related to these protective mechanisms is essential for effective metal remediation.

Insight into the endocrine disrupting effect and cell response to butyltin compounds in H295R cell: Evaluated with proteomics and bioinformatics analysis.

The widespread use of organotin compounds (OTs) as biocides in antifouling paints and agricultural applications poses a serious threat to the ecosystem and humans. Butyltin compounds (BTs), especially tributyltin (TBT), are considered to be endocrine disrupting chemicals in marine organisms. The underlying mechanism of disrupting effects on mammals, however, has not been sufficiently investigated.

Effect of silver sulfide nanoparticles on photochemical degradation of dissolved organic matter in surface water.

Silver sulfide nanoparticles (AgSNPs) have shown photocatalytic activity, yet little is known about the effect of AgSNPs on the photochemical degradation of dissolved organic matter (DOM) in surface water, which seriously impairs understanding of AgSNPs' environmental risks. Herein, this study on the basis of electrospray ionization coupled with Fourier-transform ion cyclotron resonance mass spectrometry (ESI-FTICR-MS) showed for the first time that photodegradation of natural organic matter (NOM, 2R101 N) could be accelerated by both bared and polyvinylpyrrolidone (PVP)-coated AgSNPs; the NOM with AgSNPs (e.g.

Two-dimensional (weak anion exchange chromatography-gel electrophoresis) separations coupling to inductively coupled plasma mass spectrometry strategy for analysis of metalloproteins.

A two-dimensional (2-D, weak anion exchange chromatography-gel electrophoresis, WAX-GE) separations coupling to inductively coupled plasma mass spectrometry (ICP-MS) strategy was developed for efficient tracking of metalloproteins. Samples were fractionized with the primary dimension (WAX) and the collected fractions were subsequently subjected to the secondary dimension (GE) and finally detected with ICP-MS. The metalloproteins of interest from the secondary dimension were online split and collected for further manipulation.

Antibacterial mechanism of silver nanoparticles in Pseudomonas aeruginosa: proteomics approach.

Silver nanoparticles (AgNPs) are the nanomaterials most widely used as antimicrobial agents in a range of consumer products, due to the environmental release of either the AgNPs themselves or silver ions. Although AgNPs appear to be more potent than silver ions, the mechanism behind the activity is not fully elucidated yet. The most common mechanism of toxicity of AgNPs proposed to date is the release of silver ions and/or the particle-specific functions.

Organotin exposure stimulates steroidogenesis in H295R Cell via cAMP pathway.

Organotin compounds (OTs) are used in a range of industrial products, such as antifouling paints, agricultural pesticides and stabilizers. Owing to potential endocrine-disrupting effects, human exposure to such compounds is a concern. Nevertheless, little is known about the adverse effect of OTs on adrenocortical function in organisms.

Research on Localization Algorithms Based on Acoustic Communication for Underwater Sensor Networks.

The water source, as a significant body of the earth, with a high value, serves as a hot topic to study Underwater Sensor Networks (UWSNs). Various applications can be realized based on UWSNs. Our paper mainly concentrates on the localization algorithms based on the acoustic communication for UWSNs.

Doxycycline synergizes with doxorubicin to inhibit the proliferation of castration-resistant prostate cancer cells.

Castration-resistant prostate cancer (CRPC) is fatal and there is currently no effective clinical treatment. The antibiotic doxycycline has shown anti-cancer effect in several kinds of solid tumors including prostate cancer. In this study, a combination of doxycycline and doxorubicin was used to investigate the synergistic effect on CRPC cells.

Surface ligand controls silver ion release of nanosilver and its antibacterial activity against .

Understanding the mechanism of nanosilver-dependent antibacterial activity against microorganisms helps optimize the design and usage of the related nanomaterials. In this study, we prepared four kinds of 10 nm-sized silver nanoparticles (AgNPs) with dictated surface chemistry by capping different ligands, including citrate, mercaptopropionic acid, mercaptohexanoic acid, and mercaptopropionic sulfonic acid. Their surface-dependent chemistry and antibacterial activities were investigated.

Identification and accurate size characterization of nanoparticles in complex media.

We have developed a new method for the identification and accurate size characterization of nanoparticles (NPs) in complex media based on capillary electrokinetic (CE) separation coupled to inductively coupled plasma mass spectrometry (ICP-MS). Through mass scanning and Gaussian fitting of electropherogram peaks, we can obtain multidimensional information on chemical compositions, size distributions, and ionic species of multiple NPs in a single run. The results are more accurate than those obtained by using conventional methods.