Publications by authors named "Xueting Tu"
Background: Hearing loss is highly prevalent and can have significant consequences for older adults aging with cognitive impairment. However, few older adults use hearing aids and disparities in care exist by race, ethnicity, and socioeconomic position. To understand the intersection of hearing loss and cognitive impairment with the ultimate goal of developing an affordable, accessible hearing care intervention responsive to the needs of end-users, a series of semi-structured interviews was conducted.
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- The expansion of a (GGGGCC)n repeat in the C9ORF72 gene is linked to frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), leading to abnormal RNA structures and dipeptide repeat proteins.
- This study shows that the (GGGGCC)n RNA affects the functioning of nuclear speckles, which are essential for RNA processing, by disturbing their dynamics and sequestering crucial proteins like SRRM2.
- The disruption of nuclear speckle integrity results in significant changes in RNA splicing and contributes to neuronal damage, identifying new mechanisms and potential targets for treatment in C9-FTD/ALS.
is a major cause of Vibriosis in farmed marine aquatic animals and has caused large economic losses to the Asian aquaculture industry in recent years. Therefore, it is necessary to control effectively. The virulence mechanism of , the Type III secretion system (T3SS), is closely related to its pathogenicity.
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