Publications by authors named "Xueshan Li"

A 10-week feeding trial, followed by 24-h nitrite stress, was performed to evaluate the effects of dietary selenium-L-methionine (Se-Met) on growth, Se accumulation, antioxidant capacity, transcripts of selenoproteins and histological changes of muscle as well as resistance to nitrite stress in spotted seabass () reared at optimal (27 °C) and high (33 °C) temperatures. Five experimental diets were formulated to contain 0, 0.9, 1.

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This study investigated the effect of dietary lipid levels on growth performance, lipid metabolism, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog () tadpoles. A total of six isonitrogenous diets were prepared, each containing 4.46% (L5), 6.

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  • Low phosphorus (LP) diets disrupt energy metabolism in fish, particularly affecting liver functions and mitochondrial mechanisms, which are not well understood.
  • The study involved feeding spotted seabass and zebrafish diets with varying phosphorus levels and utilizing methods like Drp1 knockdown and PKA activation to analyze molecular changes and mitochondrial health.
  • Results showed that LP diets led to significant reductions in ATP and cAMP levels, while manipulating Drp1 and PKA pathways improved energy metrics in the liver, highlighting potential interventions for energy disorders in fish.
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  • The study explored how past exacerbation history affects future exacerbations and mortality in COPD patients categorized by the GOLD A and B classifications.
  • Data was collected from 8318 COPD patients in China between 2017 and 2022, tracking their health outcomes until December 2023 or death, focusing on exacerbation events and mortality rates.
  • Results showed that patients in the GOLD E group had the highest risk of future exacerbations and mortality, while those in GOLD A1 experienced significantly increased risks compared to GOLD A0; specific inhaled corticosteroids were found to be beneficial in reducing exacerbation risks in certain groups.
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  • * Poultry by-products had the highest levels of microplastics, especially in the form of microfibers, with sizes mainly between 500 and 1000 μm.
  • * The research highlights packaging materials as major pollution sources and identifies certain fish species, like Catla catla and Oreochromis niloticus, as being at high risk for microplastic exposure, aiding in improving aquafeed quality.
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Our study aims to examine the changes of long-term high temperature on the mortality and health status of spotted seabass (Lateolabrax maculatus), as well as to screen suitable biomarkers to determine whether the spotted seabass is under heat stress. In this study, 360 juvenile spotted seabass were evenly distributed into three temperature-controlled systems at 27 °C (N, normal temperature), 31 °C (M, moderate temperature), and 35 °C (H, high temperature) for an 8-week aquaculture experiment. The results revealed that 35 °C water temperature significantly increased the mortality and the MDA content in tissues (P < 0.

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Soybean meal (SM) serves as a primary alternative to fish meal in aquafeeds. However, a high-SM diet may result in intestinal injury. Our previous study demonstrated the probiotic effects of heat-inactivated Bacillus subtilis (LCBS1) on bullfrogs (Aquarana catesbeianus) fed a high-SM diet, probably attributed to the bioactive constituent of cell wall.

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  • Researchers studied growth differences in spotted seabass on a low-phosphorus diet, using 150 fish over eight weeks to identify fast-growing (FG) and slow-growing (SG) categories based on weight.
  • Analysis of the fish livers through metabolomics and transcriptomics showed that FG had a higher antioxidant capacity, and 431 differentially expressed genes were linked to metabolism, with many involved in processes like protein digestion and substance transport.
  • The study concluded that FG exhibited enhanced liver functions related to immune response and amino acid metabolism, providing insights for improving low-phosphorus diets and selective breeding practices for spotted seabass.
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Objective: In this study, we evaluated the efficacy and safety of 1 μg/kg dexmedetomidine as an adjuvant treatment to ropivacaine in children undergoing upper limb surgeries under ultrasound-guided axillary brachial plexus blocks and general anesthesia.

Methods: We enrolled 90 children (aged 1-8 years; ASA I-II) undergoing closed reduction and internal fixation for upper extremity fractures at the Xiamen Children's Hospital and randomly assigned them to one of two groups: L (injection with 0.25% ropivacaine) or D (injection with 0.

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Nephrotic syndrome (NS) had serious complications due to hypercoagulable state in both various venous and arteries which could lead thromboembolic events. we described a case of a 41-year-old man who presented with pulmonary artery thrombosis and was diagnosed with NS. Early diagnosis and management of nephrotic syndrome may prevent the occurrence of venous thromboembolism (VTE).

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  • An 8-week study tested how different levels of dietary bile acids affected the growth, glucose metabolism, and intestinal health of spotted seabass at high temperatures (33°C).
  • Fish were fed diets with varying bile acid levels (0, 400, 800, and 1200 mg/kg), with the 800 mg/kg group showing significant growth promotion compared to the control group.
  • This dietary supplementation also improved liver glucose metabolism, enhanced intestinal structure and enzyme activities, and reduced inflammation while boosting antioxidant responses in the fish.
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  • Acetyl-CoA carboxylase (ACC) helps manage fat creation and burning in the liver, and this study looked at how low phosphorus levels affect its function.
  • In zebrafish liver cells, low phosphorus led to more fat build-up and less energy production compared to cells with enough phosphorus.
  • Using an ACC blocker improved energy production and reduced fat build-up in low phosphorus conditions, suggesting that targeting ACC could help treat liver issues related to low phosphorus.
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  • Cough is a prevalent symptom in COPD patients, affecting their clinical characteristics and treatment outcomes depending on the inhaled therapies they receive.
  • The study analyzed 906 patients, determining that 64.1% reported frequent cough, which was linked to being a current smoker and worse CAT scores.
  • Results showed that while 62% of frequent cough patients improved after treatment, those on LABA/LAMA or ICS/LABA/LAMA therapy had better outcomes, experiencing fewer exacerbations and achieving clinically significant improvements.
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A 10-week growth experiment was conducted to assess the physiological response of spotted seabass () raised at moderate (27 °C) and high temperatures (33 °C) to different dietary available phosphorus (P) levels. Five diets with available P levels of 0.35, 0.

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  • The study investigates the link between education levels and the clinical characteristics and outcomes of chronic obstructive pulmonary disease (COPD) in China, noting that many COPD patients have low education.
  • Analysis of data from over 4,000 COPD patients shows that those with low education faced worse symptoms, more frequent exacerbations, and a higher mortality rate.
  • The findings highlight the importance for healthcare providers to pay special attention to low-education COPD patients due to their increased health risks and poorer outcomes.
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Studies on marine fish showed that vegetable oils substituted for excessive fish oil increased interleukin-1β (IL-1β) production. However, whether the nucleotide-binding oligomerization domain, leucine-rich repeat-containing family, pyrin domain-containing-3 (NLRP3) inflammasome has a substantial role in fatty acid-induced IL-1β production in fish remains unclear. The associated specific mechanism is also unknown.

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Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 report revised the combined assessment, merged the C and D groups into the E group, and revised the initial inhalation therapy recommendation.

Objectives: This study aimed to analyze the future exacerbation and mortality of different inhalation therapies among patients with chronic obstructive pulmonary disease (COPD) in various groups based on the GOLD 2017 and GOLD 2023 reports.

Design: This is a multicenter and retrospective study.

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This study aimed to analyze the clinical characteristics and treatment response of patients with chronic obstructive pulmonary disease (COPD) with low body mass index (BMI). In this cross-sectional study, we enrolled patients with stable COPD from the database setup by the Second Xiangya Hospital of Central South University. We classified the patients into three groups based on BMI: low-BMI (<18.

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Purpose: This study aimed to examine the effectiveness of ultrasound-guided thoracic paravertebral block on postoperative quality of recovery in patients undergoing percutaneous nephrolithotomy.

Patients And Methods: In this randomized, double-blind, placebo-controlled trial, we enrolled patients scheduled for unilateral percutaneous nephrolithotomy. Patients were randomly allocated to receive thoracic paravertebral block either with 20 mL of 0.

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The Smartphone Addiction Scale Short Version (SAS-SV) has been widely used in research, but little is known about the measurement invariance across gender. The current study measured SAS-SV invariance between male and female college students in a sample of 1112 participants. Single- and multiple-group confirmatory factor analyses (CFAs) of smartphone addiction symptom ratings were conducted using R program with RStudio.

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  • This study analyzed the clinical characteristics, exacerbation risk, and mortality among chronic obstructive pulmonary disease (COPD) patients classified as more symptomatic, based on the GOLD 2017 guidelines.
  • The retrospective cohort included 1,729 stable COPD patients, followed for 18 months, with findings showing that more symptomatic patients experienced greater age, higher COPD assessment scores, and increased hospitalization rates.
  • Key risk factors identified for mortality included age over 65 and high COPD assessment test scores, while current smoking and previous exacerbations were linked to higher likelihood of future exacerbations.
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This study evaluated the effects of dietary methionine level and rearing water temperature on growth, antioxidant capacity, methionine metabolism, and hepatocyte autophagy in spotted seabass (Lateolabrax maculatus). A factorial design was used with six methionine levels [0.64, 0.

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This study was conducted to investigate the effects of meal (TM) replacement for fish meal (FM) on growth performance, humoral immunity, and intestinal health of juvenile large yellow croakers (). Four experimental diets were formulated by replacing FM with TM at different levels-0% (TM0), 15% (TM15), 30% (TM30), and 45% (TM45). Triplicate groups of juveniles (initial weight = 11.

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LDLR, as the uptake receptor of low-density lipoprotein, plays a crucial role in lipid metabolism. However, the detailed mechanism by which LDLR affects hepatic triglyceride (TG) accumulation has rarely been reported. Here, we found that knockdown of LDLR effectively mitigated PA-induced TG accumulation.

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This study was conducted to investigate the effects and regulation of dietary vegetable oil (VO, enriched with α-linolenic acid [ALA] and linoleic acid [LNA]) on the nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor-κB (NF-κB) pathways in large yellow croaker. In vivo study showed that the VO diet significantly decreased the activity of antioxidant enzymes and antioxidant enzyme-related mRNA expression in the liver tissue, in comparison with the fish oil (FO) diet (P < 0.05).

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