Suppression of the hole trap for high-quality amino-phosphine based InP quantum dots.

InP quantum dots (QDs) have emerged as promising nanomaterials in various fields due to their exceptional optical properties. However, its wide emission linewidth limits further application. In this study, we synthesized high-quality InP/ZnSe/ZnS QDs by suppressing hole defects.

Improving spectral linewidth performance of InP quantum dots by promoting size-focused growth and decreasing exciton-phonon coupling.

InP-based quantum dots (QDs) are widely adopted as a superior alternative to CdSe-based QDs in various fields owing to their high quantum yield, environmental friendliness, and excellent stability. However, improving its color purity remains a challenging task. In this work, we employ a multistage heating strategy to optimize the nucleation and shell growth processes of amino-phosphine-based InP/ZnSe/ZnS QDs for reducing emission linewidths.

A Small Molecule Chemiluminophore with near 600 nm Emission for In Vivo Imaging of Myeloperoxidase and Inflammatory Diseases.

Chemiluminescence has emerged as a vital tool for bioimaging in vivo. The red shift emission of chemiluminophores is extremely useful for in vivo bioimaging. In this work, the conjugation system of the luminol was extended to achieve a red-shifted emission (591 nm) along with excellent water solubility.

High Expression of SRSF10 Promotes Colorectal Cancer Progression by Aberrant Alternative Splicing of RFC5.

Background: Colorectal cancer (CRC) remains a global health concern with persistently high incidence and mortality rates. However, the specific pathogenesis of CRC remains poorly understood. This study aims to investigate the role and pathogenesis of serine and arginine rich splicing factor 10 (SRSF10) in colorectal cancer.

Generating synthetic computed tomography for radiotherapy: SynthRAD2023 challenge report.

Radiation therapy plays a crucial role in cancer treatment, necessitating precise delivery of radiation to tumors while sparing healthy tissues over multiple days. Computed tomography (CT) is integral for treatment planning, offering electron density data crucial for accurate dose calculations. However, accurately representing patient anatomy is challenging, especially in adaptive radiotherapy, where CT is not acquired daily.

The therapeutic and biomarker significance of ferroptosis in chronic myeloid leukemia.

Background: The relationship between ferroptosis and the progression and treatment of hematological tumors has been extensively studied, although its precise association with chronic myeloid leukemia (CML) remains uncertain.

Methods: Multi-transcriptome sequencing data were utilized to analyze the ferroptosis level of CML samples and its correlation with the tumor microenvironment, disease progression, and treatment response. Machine learning algorithms were employed to identify diagnostic ferroptosis-related genes (FRGs).

Designed Growth of Covalently Bonded WO/PEDOT Hybrid Nanorods Array with Enhanced Electrochromic Performance.

A covalently bonded WO/PEDOT hybrid nanorods array has been prepared through solvothermal, oil bath, and electrochemical deposition methods using KH57 as a coupling agent. The obtained WO/PEDOT shows substantially increased electrochromic performance with an increased response speed (3.4 s for coloring and 1.

The clinical value of rapidly detecting urinary exosomal lncRNA RMRP in bladder cancer with an RT-RAA-CRISPR/Cas12a method.

Background And Aims: Bladder cancer (BCa) is a highly aggressive malignancy of the urinary system. Timely detection is imperative for enhancing BCa patient prognosis.

Materials And Methods: This study introduces a novel approach for detecting long non-coding RNA (lncRNA) Mitochondrial RNA Processing Endoribonuclease (RMRP) in urine exosomes from BCa patients using the reverse transcription recombinase-aided amplification (RT-RAA) and clustered regularly interspaced short palindromic repeats and associated Cas12a proteins (CRISPR/Cas12a) technique.

Genome-wide identification analysis in wild-type reveals some genes defending against .

exhibits strong resistance to late blight caused by but only an incomplete genome assembly based on short Illumina reads has been published. In this study, we generated the first chromosome-level draft genome for the wild-type potato species in China using Oxford Nanopore technology sequencing and Hi-C technology. The high-quality assembled genome size is 664 Mb with a scaffold N50 value of 49.

Synthesis, Photophysical, and Optical Limiting Properties of Twistacene-Functionalized Arenes.

To realize the relationship of structure and property, four novel twistacene-functionalized arenes, namely, 1,4-bis(2,7-di--butyl-9,14-bis(4-(-butyl)phenyl)dibenzo[,]tetracen-11-yl)buta-1,3-diyne (), 1,4-bis(3,5,10,12-tetra--butyltribenzo[,,]coronen-16-yl)buta-1,3-diyne (), 1,4-bis(2,7-di--butyl-9,14-bis(4-(-butyl)phenyl)dibenzo[,]tetracen-10-yl)buta-1,3-diyne (), 1,4-bis(3,5,10,12-tetra--butyltribenzo[,,]coronen-15-yl)buta-1,3-diyne (), linked with butadiyne as π bridges have been strategically synthesized and characterized. The nonlinear optical properties are detailly examined in solution through the open-aperture Z-scan method in a comparative manner, indicating that molecules and exhibit better nonlinear optical responses than and . Among them, and exhibit excellent optical limiting responses with limiting thresholds of 0.

Effect of In Situ Heating on the Growth and Electrochromic Properties of Tungsten Trioxide Thin Films.

Electrochromism has emerged as a pivotal technology in the pursuit of energy efficiency and environmental sustainability, spurring significant research efforts aimed at the creation of advanced electrochromic devices. Most electrochromic materials are used for smart window applications. However, current electrochromic materials have been applied to new energy vehicles, cell phone back covers, AR glasses, and so on.

Application of interpretable machine learning algorithms to predict distant metastasis in ovarian clear cell carcinoma.

Background: Ovarian clear cell carcinoma (OCCC) represents a subtype of ovarian epithelial carcinoma (OEC) known for its limited responsiveness to chemotherapy, and the onset of distant metastasis significantly impacts patient prognoses. This study aimed to identify potential risk factors contributing to the occurrence of distant metastasis in OCCC.

Methods: Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, we identified patients diagnosed with OCCC between 2004 and 2015.

Construction of active-inert core-shell structured nanocrystals for broad range multicolor upconversion luminescence.

Rare earth doped up-conversion luminescent nano-materials exhibit abundant emission colors under suitable excitation condition. In this work, NaYF:Er/Ho@NaYF and NaYbF:Tm@NaYF nanoparticles were synthesized by co-precipitation method. The pure red emission can be realized by the designed NaYF:Er/Ho@NaYF nanocrystals and the R/Gs reach 23.

Correlation of Folic Acid Metabolic Gene Polymorphisms, Homocysteine, Vitamin B12, and Red Blood Cell Folate with Adverse Pregnancy Outcomes.

Objective: This study aims to investigate the relationship between folic acid (FA) metabolic gene polymorphisms, homocysteine (Hcy), vitamin B12 (Vit B12), and red blood cell folate (RBCF) with adverse pregnancy. The findings of this study can help in the prevention and treatment of adverse pregnancy in the future.

Methods: 118 pregnant women admitted to Qingdao Central Hospital between August 2020 and October 2022 were selected for retrospective analysis, including 62 cases of normal delivery (control group, CG) and 56 cases of adverse pregnancy (research group, RG).

Associations between triglyceride glucose index and depression in middle-aged and elderly adults: A cross-sectional study.

The pathogenesis of depression is unclear, and it responds poorly to treatment. It is thus urgent to identify the pathogenesis of depression and possible therapeutic targets. There may be interactions between insulin resistance (IR) and depression.

PH13 improves soybean shade traits and enhances yield for high-density planting at high latitudes.

Shading in combination with extended photoperiods can cause exaggerated stem elongation (ESE) in soybean, leading to lodging and reduced yields when planted at high-density in high-latitude regions. However, the genetic basis of plant height in adaptation to these regions remains unclear. Here, through a genome-wide association study, we identify a plant height regulating gene on chromosome 13 (PH13) encoding a WD40 protein with three main haplotypes in natural populations.

Association of triglyceride-glucose index with major depressive disorder: A cross-sectional study.

The triglyceride-glucose (TyG) index has been proposed as a new marker for insulin resistance, which is associated with a risk of major depressive disorder (MDD). This study aims to explore whether the TyG index is correlated with MDD. In total, 321 patients with MDD and 325 non-MDD patients were included in the study.

Fairness and Accuracy Under Domain Generalization.

As machine learning (ML) algorithms are increasingly used in high-stakes applications, concerns have arisen that they may be biased against certain social groups. Although many approaches have been proposed to make ML models fair, they typically rely on the assumption that data distributions in training and deployment are identical. Unfortunately, this is commonly violated in practice and a model that is fair during training may lead to an unexpected outcome during its deployment.

A fair and interpretable network for clinical risk prediction: a regularized multi-view multi-task learning approach.

In healthcare domain, complication risk profiling which can be seen as multiple clinical risk prediction tasks is challenging due to the complex interaction between heterogeneous clinical entities. With the availability of real-world data, many deep learning methods are proposed for complication risk profiling. However, the existing methods face three open challenges.

Ultrafast nonlinear absorption with multiple transformations and transient dynamics of gold nanobipyramids.

The process and condition of saturable absorption (SA) and reverse saturable absorption (RSA) of ultrafast nonlinear optics in metal nanoparticles are essential for applications including light generation, amplification, modulation, and switching. Here, we first discover and explore the multiple transformations (SA-RSA-SA) of ultrafast nonlinear absorption behavior of metal nanoparticles in femtosecond pulses. Correspondingly, the energy level model and fitting formula of multiple transformations are established to illustrate the process of optical response.

Ferroptosis-related molecular patterns reveal immune escape, inflammatory development and lipid metabolism characteristics of the tumor microenvironment in acute myeloid leukemia.

Background: An increasing number of studies have revealed the influencing factors of ferroptosis. The influence of immune cell infiltration, inflammation development and lipid metabolism in the tumor microenvironment (TME) on the ferroptosis of tumor cells requires further research and discussion.

Methods: We explored the relationship between ferroptosis-related genes and acute myeloid leukemia (AML) from the perspective of large sample analysis and multiomics, used multiple groups to identify and verify ferroptosis-related molecular patterns, and analyzed the sensitivity to ferroptosis and the state of immune escape between different molecular pattern groups.

Palladium (II), platinum (II) and silver (I) complexes with oxazolines: Their synthesis, characterization, DFT calculation, molecular docking and antitumour effects.

Six new Pd(II), Pt(II) and Ag(I) complexes, (1);{Pd (L)]2CH}Cl} (2); Pt(L)(DMSO)Cl; 3; {PtL]CH}·PhCOO⋅11NO; 4; {[Pt(L)]CH}; the binuclear cyclometalated complex the polymer chain (5); {[PtL]CH}·NO}; and the polymeric silver species (6); Zn(L)·AgNO·CHCl were synthesized and thoroughly characterized using X-ray diffraction and spectroscopic techniques (L=(S,S)-1,4-i-PrOx]CH}Cl, L=Di(2,2-bis(4R-isopropyl-4,5-dihydro-oxazol-2-yl)acetonitrile) zinc (II) (B);L= 1,4-bis(4R-benzyl-4,5-dihydro-oxazol-2-yl)benzene (A); L= 1,4-bis(4R-benzyl-4,5-dihydro-oxazol-2-yl)benzene，L=1,4-bis(4R-benzyl-4,5-dihydro-oxazol-2-yl)-benzene，L=Di(2,2-bis(4S-isopropyl-4,5-dihydrooxazol-2-yl)acetonitrile) zinc (II). Complexes 1-6 showed cytotoxic effects against human tumour cell lines, including a multidrug-resistant subline. Oxazoline and Pd complex 1 induced apoptosis in A549 cells.

High-sensitive temperature sensing based on thermal-enhanced emission and non-thermally coupled energy levels of white upconversion luminescence system.

NaY(VO):Nd,Yb,Ho,Tm phosphors present significantly improved sensitivity of optical temperature sensing based on thermal-enhanced upconversion luminescence and non-thermally coupled energy levels. Under 808 nm excitation, white upconversion luminescence is successfully achieved in Nd-sensitized system. In addition, the emissions intensities originated from G→I transition of Nd and F→H transition of Tm gradually increase with elevating temperature owning to the thermal population effects, as opposed to the blue (G→H transition of Tm), green (S,F→I transition of Ho) and red (F→I transition of Ho) emissions intensities show continuous decreasing trend.

Synthesis and Ultrafast Broadband Optical Limiting Properties of a Two-Branched Twistacene.

A novel two-branched twistacene () has been designed and synthesized for application on ultrafast optical limiting. This twistacene exhibits excellent two photon absorption and two photon absorption-induced excited singlet state absorption, which was systematically investigated with a femtosecond Z-scan experiment, transient absorption spectrum, and two-photon excited fluorescence experiments. The admirable two photon absorption is attributed to the high degree of π electron delocalization in twistacene which is caused by introduction of two strong donors.